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Telogen effluvium

life science Maturity 11-13 Next article →

Telogen effluvium is a scalp disorder that causes hair thinning or shedding. This condition occurs when hair follicles enter the telogen phase too early. The telogen phase is the resting stage of the hair follicle. Under normal conditions, humans lose about 125 hairs per day. This daily loss is a standard part of the hair cycle. It typically has no effect on a person's overall appearance. However, in telogen effluvium, hairs shed at a much higher rate than usual.

There are five specific ways the hair cycle can change to cause this. The first is immediate anagen release. This happens when follicles leave the anagen, or growing, phase prematurely. The stimulation to enter the telogen phase happens too soon. These effects usually become visible two to three months after the initial change.

The second type is delayed anagen release. This is most commonly associated with pregnancy. During pregnancy, hormones can prolong the anagen phase. This causes the hair to stay in the growing stage longer than usual. When the pregnancy ends, it results in synchronous and heavy postpartum hair shedding.

Short anagen syndrome is the third type. This involves a shortening of the duration of the anagen phase. Because the growing phase is shorter, a greater number of hairs are in the telogen phase at any one time. This makes it difficult to grow hair long. This mechanism is responsible for the majority of chronic cases of telogen effluvium.

The fourth type is immediate telogen release. This often occurs due to certain drugs that shorten the telogen phase. For example, the drug minoxidil can precipitate this reaction. When the telogen phase is shortened, follicles reenter the anagen phase prematurely. This process causes a massive release of club hairs, which are hairs in the telogen stage.

The fifth type is delayed telogen release. In this case, the telogen phase is prolonged. This leads to a delayed transition back to the anagen phase. This pattern is seen in animals with synchronous hair cycles. It helps them shed their winter coats during specific seasons. Humans may also experience similar seasonal hair loss.

Many factors can trigger these changes in the hair cycle. Emotional or physiological stress is a major cause. This includes major surgery, chronic illness, or severe emotional disorders. Physical causes include eating disorders, crash diets, and anemia. Hypothyroidism is another medical cause. Pregnancy and childbirth are also significant factors.

Doctors use several diagnostic tests to verify a diagnosis of telogen effluvium. They may perform a trichogram or use trichoscopy to examine the hair. They might also perform a biopsy, which is taking a small sample of the scalp. This helps distinguish the disorder from alopecia totalis. In telogen effluvium, histology shows telogen hair follicles in the dermis with minimal inflammation. In contrast, alopecia totalis shows a dense peribulbar lymphocytic infiltrate.

Some cosmetic treatments can help manage the appearance of thinning hair. One combination uses caffeine, niacinamide, panthenol, dimodimethicone, and an acrylate polymer. This is known as CNPDA technology. This treatment can increase the diameter of individual hair fibers by 2 to 5 micrometers. This results in an increase of approximately 10% in the cross-sectional area of each hair. These thickened hairs also show better mechanical properties. They have increased suppleness and a better ability to withstand force without breaking.

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