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Sleep disorder

life science Maturity 11-13 Next article →

A sleep disorder, also known as a somnipathy, is a medical condition that disrupts sleep patterns and quality. These disturbances can harm a person's physical, mental, and emotional well-being. To diagnose these issues, doctors often order specific medical tests. One common test is polysomnography, which monitors various body functions during sleep. Another tool is actigraphy, which tracks movement patterns.

Room for sleep studies - NÄL hospital
Room for sleep studies - NÄL hospital

Understanding these disorders is vital for maintaining overall health.

Sleep disorders are broadly classified into several distinct categories. Dyssomnias and parasomnias are two major groups. There are also circadian rhythm sleep disorders, which involve the body's internal clock. Other disorders may stem from specific medical or psychological conditions. Insomnia is the most common type of sleep disorder. It occurs when a person struggles to fall or stay asleep without an obvious reason. Other examples include narcolepsy, sleepwalking, and night terrors.

2023 CDC recommendations for amount of sleep needed, by age
2023 CDC recommendations for amount of sleep needed, by age

Many different factors can trigger the onset of a sleep disorder. Lifestyle changes and environmental changes are common contributors. Increased use of medication and high levels of stress also play roles. Age-related changes in circadian rhythms are significant for older adults. The risk for certain conditions is especially high in the elderly. These include restless legs syndrome and periodic limb movements. Sleep-disordered breathing and insomnia are also frequent in this age group. Some disorders may even be hereditary. A study of 632 participants looked at idiopathic REM sleep behavior disorder. Researchers found that people with this disorder often had a first-degree relative with the same issue.

Certain medical conditions can directly cause or worsen sleep issues. Obstructive sleep apnea is a common condition affecting 10% to 20% of middle-aged and older adults. It is characterized by repeated pauses in breathing during sleep. This leads to poor sleep quality and excessive daytime sleepiness. Factors like obesity and narrow airways can cause this airway collapse. Additionally, people who have experienced a traumatic brain injury are at higher risk. They are disproportionately likely to develop narcolepsy or obstructive sleep apnea.

To Sleep Forevermore
To Sleep Forevermore

Neurodegenerative diseases are closely linked to various sleep disturbances. These diseases often involve the abnormal accumulation of a protein called alpha-synuclein. This is seen in conditions like Parkinson's disease (PD) and multiple system atrophy. In people with Parkinson's disease, about 70% experience insomnia. Over 50% deal with hypersomnia, which is excessive sleepiness. Around 40% of the PD population experiences REM sleep behavior disorder. This disorder is linked to increased motor symptoms. These sleep issues can place a heavy burden on caregivers and relatives.

Alzheimer's disease (AD) also shows a strong connection to sleep problems. About 45% of people with AD have sleep disturbances, though caregiver reports suggest this may be 70%. These patients often face changes in their sleep architecture. This means the structure of their sleep stages changes significantly. They may experience reduced slow-wave sleep (SWS) and shorter REM sleep. They might also face increased restlessness or agitation known as sundowning. These changes are often linked to the accumulation of beta-amyloid and tau proteins.

The brain uses sleep to perform a vital cleaning process. This is called glymphatic clearance, which happens during NREM slow-wave sleep. This system helps degrade beta-amyloid residues to prevent plaque formation. During waking hours, metabolic activity and oxidative stress increase beta-amyloid production. Without enough sleep, these residues build up into plaques. This process often begins in the hippocampus, a brain structure essential for long-term memory. Poor sleep also interferes with neurogenesis, the production of new neurons. When neurogenesis is suppressed, memory performance can decline. This creates a bidirectional loop where sleep disorders and Alzheimer's disease worsen each other.

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