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Scar

life science Maturity 11-13 Next article →

A scar is a patch of fibrous tissue. It replaces normal skin after an injury occurs. This is a natural part of how the body repairs itself. Most wounds from accidents, diseases, or surgeries result in some scarring.

Novak 7 (5451438566)
Novak 7 (5451438566)

Some animals can regrow tissue perfectly without any scars at all. However, most humans and other mammals heal by making scar tissue. This tissue is different from the skin we are born with. It helps close a wound, but it works differently than healthy skin.

To understand how it works, we look at a protein called collagen. In normal skin, collagen fibers look like a messy basketweave. When a wound heals, the body uses cells called fibroblasts to patch the damage. These cells create a dense collagen matrix to fill the gap. In a scar, these fibers line up in a single direction.

Key processes contributing to the quasi-neoplastic expression of keloid pathobiology
Key processes contributing to the quasi-neoplastic expression of keloid pathobiology

This alignment makes the tissue stiff and less stretchy. Because of this, scars do not have hair follicles or sweat glands.

Scientists and doctors have studied these different types of healing for a long time. For example, we know that wounds smaller than 2mm usually heal without a scar. We also know that mechanical stress can make scarring worse. In 2011, researchers found that stress on a wound stimulates more scarring. By 2021, scientists found that using chemicals to stop cells from sensing stress helped wounds heal without scars.

scar revision
scar revision

These discoveries help us understand how to treat injuries better.

There are several specific types of scars you might see. Hypertrophic scars are raised, red lumps that stay within the original wound area. Keloid scars are more serious because they can grow much larger than the injury. They are most common in people with dark skin and often appear on the chest or shoulders.

Key processes contributing to the quasi-neoplastic expression of keloid pathobiology
Key processes contributing to the quasi-neoplastic expression of keloid pathobiology

Atrophic scars are sunken or pitted in the skin. These often happen when underlying fat or muscle is lost. Stretch marks, or striae, are also a form of scarring caused by rapid stretching.

Scars connect to many parts of our lives and bodies. Even your belly button is a scar from when your umbilical cord was cut. Some people use medical treatments to help with scars. For instance, chemical peels can help with superficial acne scars. Doctors can also use filler injections to raise sunken atrophic scars.

Atrophic scar of Ehlers Danlos syndrome
Atrophic scar of Ehlers Danlos syndrome

While scars can sometimes be itchy or painful, they are a sign that your body is working hard to keep you safe.

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Novak 7 (5451438566).jpg
File:Atrophic scar of Ehlers Danlos syndrome.jpg
Atrophic scar of Ehlers Danlos syndrome.jpg
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Key processes contributing to the...
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scar revision.jpg
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