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Mitosis

life science Maturity 7-9 Next article →

Have you ever wondered how your body grows or how it fixes itself? It all starts with a tiny process called mitosis.

Animal cell cycle-en
Animal cell cycle-en

Mitosis is a special part of the cell cycle. It is how one cell divides to make two new daughter cells. These new cells are genetically identical to the original parent cell. This means they have the exact same instructions inside them. This process is vital because it keeps life stable as cells divide.

Mitosis vs Meiosis Daughter Cells
Mitosis vs Meiosis Daughter Cells

Before mitosis can happen, the cell must prepare through a stage called interphase. During the S phase of interphase, the cell makes a copy of its DNA. This DNA is organized into structures called chromosomes.

CONDENSING CHROMOSOMES 2
CONDENSING CHROMOSOMES 2

Once ready, mitosis begins with prophase. The chromosomes condense and become thick and visible. In animal cells, the nuclear envelope breaks down. Then, in prometaphase, tiny fibers called microtubules attach to the chromosomes. These fibers pull the chromosome copies to opposite sides of the cell.

Prophase diagram
Prophase diagram

People have studied cell division for a very long time. In 1835, a German botanist named Hugo von Mohl described how cells divide in green algae. Later, in 1875, a Polish scientist named Wacław Mayzel described mitosis in animal cells. He saw it happening in the cells of frogs, rabbits, and cats.

Stages of early mitosis in a vertebrate cell with micrographs of chromatids
Stages of early mitosis in a vertebrate cell with micrographs of chromatids

In 1882, Walther Flemming gave the process its name, mitosis. The name comes from a Greek word meaning "warp thread." This name describes how the chromosomes look as they pull apart.

There are many specific details to learn about this process. During metaphase, the chromosomes line up in the middle of the cell. In anaphase, the sister chromatids are pulled apart to opposite ends.

Metaphase during Mitosis
Metaphase during Mitosis

After this, telophase occurs as new nuclei form. Finally, cytokinesis divides the rest of the cell. In animal cells, the membrane pinches inward to split the cell. In plant cells, a new cell plate forms in the middle.

Cytokinesis illustration
Cytokinesis illustration

If errors happen, it can lead to problems like cancer or non-viable embryos.

Mitosis works differently depending on the type of living thing. For example, most animal cells undergo an "open" mitosis where the nucleus breaks down. However, fungal cells often have a "closed" mitosis where the nucleus stays intact.

Types of mitosis int
Types of mitosis int

Bacteria and archaea do not use mitosis at all. Instead, they use a different way to divide called binary fission. Most human cells are made through mitosis, but there are exceptions. Your sperm and egg cells are made through a different process called meiosis.

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🖼️ Images & Media (16)
File:Animal cell cycle-en.svg
Animal cell cycle-en.svg
Mitosis drosophila larva.ogv
File:Stages of early mitosis in a vertebrate cell with micrographs of chromatids.svg
Stages of early mitosis in a vertebrate...
File:CONDENSING CHROMOSOMES 2.jpg
CONDENSING CHROMOSOMES 2.jpg
File:Prophase diagram.svg
Prophase diagram.svg
File:Mitosis-fluorescent.jpg
Mitosis-fluorescent.jpg
File:Metaphase during Mitosis.svg
Metaphase during Mitosis.svg
File:Anaphase during Mitosis.svg
Anaphase during Mitosis.svg
File:Telophase during Mitosis.svg
Telophase during Mitosis.svg
File:Cytokinesis illustration.svg
Cytokinesis illustration.svg
File:Unk.cilliate.jpg
Unk.cilliate.jpg
File:Atypical mitosis.jpg
Atypical mitosis.jpg

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