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Measles

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Measles is a highly contagious infectious disease caused by the measles virus.

Measles virus
Measles virus

This virus belongs to the genus Morbillivirus within the Paramyxoviridae family. It is a single-stranded, negative-sense, enveloped RNA virus. While it is often thought of as a childhood illness, it can affect people of any age. Humans are the only natural hosts for this virus, though mountain gorillas may be susceptible. Because it spreads so easily, it is considered one of the most contagious human pathogens. Understanding how it moves through a community is vital for public health.

The virus spreads primarily through the air. When an infected person coughs or sneezes, they release respiratory droplets. These droplets can remain suspended in the air for up to two hours.

MeaslesOsmosisPic5
MeaslesOsmosisPic5

A person can also catch measles through direct contact with nasal or mouth secretions. The virus is extremely efficient at spreading. If nine out of ten non-immune people share a living space with an infected person, nine of them will likely become infected. This high rate of transmission makes it difficult to contain without high levels of community immunity.

Symptoms typically appear 10 to 14 days after a person is exposed to the virus. The illness often begins with a prodrome, which is an early set of symptoms. These include a fever that increases in a stepwise fashion, a cough, a runny nose, and inflamed eyes. This group of symptoms is often called "the three C's": cough, coryza (a head cold), and conjunctivitis.

Measles Illustration IMG
Measles Illustration IMG

Two to three days after symptoms start, small white clusters called Koplik spots may appear inside the mouth. These spots look like grains of salt on reddened areas near the molars. They are a specific sign used to identify measles.

A few days after the initial symptoms, a characteristic red, flat rash appears. This maculopapular rash usually starts on the face or behind the ears. It then spreads downward to cover the rest of the body.

Measles Illustration IMG
Measles Illustration IMG

As the rash heals, it may "stain" by changing from red to a dark brown color. While many cases are uncomplicated and resolve within 7 to 10 days, the virus can cause serious complications. These occur in about 30% of cases and are often caused by the virus's effect on the immune system.

Common complications include diarrhea, which affects 8% of cases, and middle ear infections, which affect 7%. Pneumonia is another common complication, occurring in about 6% of patients.

Morbillo
Morbillo

More severe issues include encephalitis, which is inflammation of the brain, and blindness caused by corneal ulceration. The virus can also cause "immune amnesia." This happens because the virus destroys memory lymphocytes, which are cells that help the body remember how to fight previous germs. This leaves the immune system weakened for two to three years, increasing the risk of other infections.

History shows how much global health efforts have changed the impact of this disease. In 1980, approximately 2.6 million people died from measles. By 1990, that number fell to 545,000.

Measles vaccination coverage world
Measles vaccination coverage world

Through global vaccination programs, the death toll dropped to 73,000 by 2014. However, because vaccination rates have decreased since 2017, deaths have begun to rise again. In the United States, between 1985 and 1992, the death rate was 0.2%. In areas with high malnutrition, the fatality rate can reach as high as 10% or even 28%.

There is no specific treatment to cure the measles virus once a person is infected. Doctors instead provide supportive care to manage symptoms. This includes using oral rehydration solutions to prevent dehydration and providing healthy food.

Measles vaccination coverage world
Measles vaccination coverage world

Vitamin A supplementation is also recommended for children under age five. If secondary bacterial infections like pneumonia occur, doctors may prescribe antibiotics. The most effective way to prevent the disease is through the measles vaccine. To achieve herd immunity and protect the whole community, more than 95% of the population must be vaccinated.

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En.Wikipedia-VideoWiki-Measles.webm
File:Measles Illustration IMG.jpg
Measles Illustration IMG.jpg
File:Measles virus.JPG
Measles virus.JPG
File:MeaslesOsmosisPic5.jpg
MeaslesOsmosisPic5.jpg
File:Morbillo.jpg
Morbillo.jpg
File:Measles vaccination coverage world.svg
Measles vaccination coverage world.svg
File:reported cases of measles, World, 2023 (cropped).svg
reported cases of measles, World, 2023...
File:Measles in England & Wales1940-2017.png
Measles in England & Wales1940-2017.png
File:Measles US 1938-2019.png
Measles US 1938-2019.png
File:Measles Aztec drawing.jpg
Measles Aztec drawing.jpg
File:Hilleman-Walter-Reed.jpeg
Hilleman-Walter-Reed.jpeg
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