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Rinderpest

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Rinderpest was a devastating infectious disease that targeted many species of even-toed ungulates. The name comes from a German word meaning "cattle plague." While it heavily impacted cattle and domestic water buffalo, it also affected wild animals like giraffes, bison, antelope, deer, and wildebeests.

Rinderpest milk fever
Rinderpest milk fever

In populations that had no prior immunity, the mortality rate was extremely high, often approaching 100 percent. This made it one of the most significant animal diseases in history.

The disease was caused by the rinderpest virus, or RPV. This virus belongs to the genus Morbillivirus. This genus also includes the canine distemper virus and the measles virus. Scientists believe the rinderpest virus and the measles virus shared a common ancestor. A 2020 study used a 1912 measles virus genome to estimate they diverged around the 6th century BC. This timing coincided with the rise of large human settlements.

Rinderpest 1896-CN
Rinderpest 1896-CN

Understanding how the virus spreads is key to seeing how it moved so quickly. RPV is a negative-sense single-stranded RNA virus. It is an enveloped virion, meaning it has a protective outer layer. However, this virus is quite fragile in the environment. It is quickly inactivated by sunlight, heat, or desiccation, which is the process of drying out. Despite this fragility, the virus spread through direct contact between animals. It could also move through the air or via contaminated drinking water.

The progression of the disease followed a specific, dangerous pattern. First, an animal enters an incubation period lasting 3 to 15 days. During this time, the animal is infected but shows no outward signs of illness. This delay allowed infected animals to travel far from the original site. Once the clinical signs appeared, the animal suffered from fever and loss of appetite. Nasal and eye discharges were common initial symptoms.

Veterinary Report on the cattle plague, 1865-7, Great Britain Wellcome L0002361
Veterinary Report on the cattle plague, 1865-7, Great Britain Wellcome L0002361

As the infection progressed, more severe symptoms emerged. Irregular erosions, or sores, appeared in the mouth, the nose lining, and the genital tract. Animals also experienced acute diarrhea, which was often preceded by constipation. Most animals died within 6 to 12 days after these symptoms first manifested. Because of this timeline, outbreaks could spread rapidly through herds.

Runderpest in Nederland 18e eeuw
Runderpest in Nederland 18e eeuw

Human history is full of attempts to control these outbreaks. In the 18th century, Europe faced several long panzootics, which are large-scale animal epidemics. Responses varied by country. The Dutch and Germans used quarantines and strict burial practices. In England and parts of Italy, authorities chose to slaughter infected animals. In the Austrian Netherlands, officials used inspections and provided compensation to owners.

19th century print rinderpest
19th century print rinderpest

Early efforts to use inoculation saw mixed results. In the 1700s, some doctors thought rinderpest was similar to smallpox. While some trials failed or caused more disease circulation, others provided breakthroughs. A Dutch farmer named Geert Reinders worked with Wijnold Munniks to improve methods. Reinders focused on inoculating calves using maternally derived immunity. Between 1777 and 1781, his method resulted in an 89 percent survival rate. This was much higher than the 29 percent survival rate seen from natural infection.

In the 19th century, massive outbreaks continued to challenge nations. In 1865, a major outbreak hit the British Isles for three years. The British government ordered the slaughter of affected cattle. By May 1867, approximately 75,000 cattle had been slaughtered. This was a massive economic loss, with cattle valued at about £10 per head at the time.

Veterinary Report on the cattle plague, 1865-7, Great Britain Wellcome L0002361
Veterinary Report on the cattle plague, 1865-7, Great Britain Wellcome L0002361

Ultimately, rinderpest was defeated through global cooperation. A worldwide eradication campaign began in the mid-20th century. The last confirmed case was diagnosed in 2001. In 2010, the Food and Agriculture Organization of the United Nations announced that field activities were ending. In June 2011, rinderpest was formally declared eradicated. It is only the second disease in history to be completely wiped out, following smallpox.

The National Archives UK - CO 1069-28-39
The National Archives UK - CO 1069-28-39
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🖼️ Images & Media (9)
File:Rinderpest milk fever.jpg
Rinderpest milk fever.jpg
File:Runderpest in Nederland 18e eeuw.jpg
Runderpest in Nederland 18e eeuw.jpg
File:Veterinary Report on the cattle plague, 1865-7, Great Britain Wellcome L0002361.jpg
Veterinary Report on the cattle plague,...
File:Rinderpest 1896-CN.jpg
Rinderpest 1896-CN.jpg
File:Political Map of South Africa drawn 1897 reprint 1899.jpg
Political Map of South Africa drawn 1897...
File:19th century print rinderpest.jpg
19th century print rinderpest.jpg
File:Animals in action; studies and stories of beasts, birds and reptiles; their habits, their homes and their peculiarities (1901) (14755107632).jpg
Animals in action; studies and stories of...
File:The National Archives UK - CO 1069-28-39.jpg
The National Archives UK - CO 1069-28-39.jpg
File:Rinderpest memorial Mukteshwar.jpg
Rinderpest memorial Mukteshwar.jpg
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