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Lipid

life science Maturity 11-13 Vital Level 3 Next article →

Lipids are a very large group of organic molecules.

Common lipid types
Common lipid types

They include many different things like fats, waxes, and oils. They also include vitamins like A, D, E, and K. Lipids are important because they do many jobs for living things. They help store energy for later use. They also act as signals in the body. Another big job is acting as structural components for cell membranes.

Phospholipids aqueous solution structures
Phospholipids aqueous solution structures

Some lipids are hydrophobic, which means they do not mix with water. Other lipids are amphiphilic. This means they have one part that likes water and one part that does not. This special nature allows them to form structures like vesicles or membranes in water.

There are many ways these molecules work. Many lipids are made from two different building blocks. These are called ketoacyl and isoprene groups. One group of lipids is called fatty acyls. These are made of a long carbon chain. The chain can be between four and 24 carbons long.

Prostacyclin-2D-skeletal
Prostacyclin-2D-skeletal

If the chain has a double bond, it can bend. This bending helps make cell membranes stay fluid. Another group is glycerolipids. The most common type is the triglyceride.

Fat triglyceride shorthand formula
Fat triglyceride shorthand formula

These are made of glycerol and fatty acids. They are the main way animals store fat in their tissues.

People have studied lipids for a long time. In 1815, Henri Braconnot put lipids into two groups. He called them suifs, which are solid greases, and huiles, which are fluid oils. In 1823, Michel Eugène Chevreul made a longer list. He included waxes, resins, and essential oils. In 1827, William Prout realized that fat is an important nutrient.

Geraniol structure
Geraniol structure

Later, scientists found new kinds of lipids. Theodore Gobley discovered phospholipids in 1847. He called them lecithins. He found them in the brains of mammals and in hen eggs. In 1923, Gabriel Bertrand introduced the word "lipide." This word was later changed to the English word "lipid."

Scientists use many categories to group these molecules. The Lipid MAPS consortium uses eight different categories. These include fatty acyls, glycerolipids, and glycerophospholipids.

They also include sphingolipids, saccharolipids, and polyketides. The last two groups are sterol lipids and prenol lipids.

Cholesterol
Cholesterol

Phospholipids are very important for cells. They are key parts of the lipid bilayer. This is the double layer that makes up cell membranes. Some phospholipids, like phosphatidylcholine, are found everywhere in nature. Other types, like sphingomyelins, are found in the brains of mammals.

Sphingomyelin-horizontal-2D-skeletal
Sphingomyelin-horizontal-2D-skeletal

Lipids are all around us in daily life. We see them in the food we eat every day. They are used in the cosmetic industry to make creams. They are even used in nanotechnology.

Kdo2-lipidA
Kdo2-lipidA

Some lipids, called sterols, are very famous. Cholesterol is a well-known sterol. It is a part of cell membranes. Plants have their own versions called phytosterols. Fungi use a different kind called ergosterol. Even though our bodies use lipids for many things, we cannot make them all. Humans must get some essential lipids from the food we eat.

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🖼️ Images & Media (10)
File:Common lipid types.svg
Common lipid types.svg
File:Prostacyclin-2D-skeletal.png
Prostacyclin-2D-skeletal.png
File:Leukotriene B4.svg
Leukotriene B4.svg
File:Fat triglyceride shorthand formula.PNG
Fat triglyceride shorthand formula.PNG
File:Phosphatidyl-ethanolamine.svg
Phosphatidyl-ethanolamine.svg
File:Sphingomyelin-horizontal-2D-skeletal.png
Sphingomyelin-horizontal-2D-skeletal.png
File:Cholesterol.svg
Cholesterol.svg
File:Geraniol structure.png
Geraniol structure.png
File:Kdo2-lipidA.png
Kdo2-lipidA.png
File:Phospholipids aqueous solution structures.svg
Phospholipids aqueous solution structures.svg
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