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Kidney stone disease

life science Maturity 11-13 Next article →

Kidney stones are hard masses that form inside the urinary tract. This condition is known as kidney stone disease or urinary stone disease. It happens when there are too many minerals in the urine. This usually occurs when there is not enough liquid or hydration. These minerals can turn into tiny crystals that clump together. These clumps eventually grow into hard pieces called calculi.

Blausen 0595 KidneyStones
Blausen 0595 KidneyStones

Scientists call this a crystallopathy. It is a common problem for many people around the world.

Stones form through a specific way it works in three steps. First, a process called nucleation creates tiny seed crystals. This happens when the urine is supersaturated with minerals. Supersaturated means the liquid holds more substances than it can normally carry. Next, the stones go through a growth phase. The single crystals expand and get larger. Finally, aggregation happens when many crystals clump together into a mass.

Staghorn Kidney Stone Progression
Staghorn Kidney Stone Progression

These stones can grow quite large over time.

People have dealt with these stones for a very long time. Descriptions of surgery to remove them are quite old. A person named Sushruta performed these surgeries in ancient India. This was as early as 600 BC. Today, we know much more about why they form. We know that genetics and environmental factors play a role. Many people find that they develop another stone within ten years.

Lithiase rénale avec dilatation du bassinet et des calices
Lithiase rénale avec dilatation du bassinet et des calices

There are many different types of stones. The most common type is calcium oxalate. Other types include uric acid, struvite, or cystine.

Calcium oxalate crystal
Calcium oxalate crystal

In 2015, there were about 22.1 million cases of kidney stones. This resulted in about 16,100 deaths. Between 1% and 15% of people globally are affected at some point. Most men between the ages of 40 and 60 are affected. The number of cases is rising worldwide.

If a stone is small, it might pass without any symptoms. However, larger stones can cause a blockage in the ureter. This leads to renal colic, which is very sharp pain. This pain often moves from the back to the groin.

Pos-renal
Pos-renal

Doctors can use medicine to help manage the pain. For larger stones, they may use a lithotriptor machine. This machine uses waves to break the stone apart.

Lithotriptor machine
Lithotriptor machine

Drinking plenty of water is a great way to help prevent them.

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🖼️ Images & Media (18)
File:Pos-renal.png
Pos-renal.png
File:Kidney stone composed of calcium oxalate showing sharp edges.jpg
Kidney stone composed of calcium oxalate...
File:Staghorn Kidney Stone Progression.png
Staghorn Kidney Stone Progression.png
File:Struvite crystals dog with scale 1.JPG
Struvite crystals dog with scale 1.JPG
File:Calcium oxalate crystal.jpg
Calcium oxalate crystal.jpg
File:Calcium phosphate crystal.jpg
Calcium phosphate crystal.jpg
File:Uric acid crystal.jpg
Uric acid crystal.jpg
File:Struvite crystals.jpg
Struvite crystals.jpg
File:Cystine crystals.jpg
Cystine crystals.jpg
File:Surface of a kidney stone.jpg
Surface of a kidney stone.jpg
File:Kidney stones, Uric acid.JPG
Kidney stones, Uric acid.JPG
File:Lenticular kidney stone.jpg
Lenticular kidney stone.jpg

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