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Human skin

life science Maturity 9-11 Next article →

Human skin is the largest organ of the integumentary system. It serves as the body's primary outer covering. This organ protects muscles, bones, ligaments, and internal organs. It acts as a vital shield against pathogens and excessive water loss. The skin also manages insulation and temperature regulation. It facilitates sensation and the synthesis of vitamin D. It even helps protect vitamin B folates.

06 Hegasy Skin Layers Receptors Wiki EN CCBYSA
06 Hegasy Skin Layers Receptors Wiki EN CCBYSA

The skin is composed of three primary layers. These are the epidermis, the dermis, and the hypodermis. The epidermis is the outermost layer. Its name comes from the Greek word for "over" or "upon." The dermis sits directly beneath the epidermis. It provides cushioning and contains many vital structures. The hypodermis, or subcutaneous tissue, lies below the dermis. It is not technically part of the skin itself. It attaches the skin to underlying bone and muscle.

06 Hegasy Skin Layers Receptors Wiki EN CCBYSA
06 Hegasy Skin Layers Receptors Wiki EN CCBYSA

The epidermis works through a process called keratinization. This process begins at the basal layer. Here, new cells are formed through mitosis. These daughter cells move upward through different strata. These layers include the stratum corneum, lucidum, granulosum, spinosum, and basale. As cells move up, they change shape and composition. They eventually lose their cytoplasm and incorporate the protein keratin. The stratum lucidum is only found in palms and soles. Finally, the cells reach the corneum and slough off. This waterproof barrier prevents infection and keeps water inside the body.

The dermis is a thick layer of connective tissue. It is held to the epidermis by a basement membrane. The dermis is divided into two distinct regions. The superficial area is the papillary region. It features finger-like projections called papillae. These papillae interdigitate with the epidermis to strengthen the connection. In the hands and feet, these projections form epidermal ridges. These ridges create unique fingerprints and footprints. The deeper area is the reticular region. It contains a dense concentration of collagen, elastin, and reticular fibers. These fibers provide strength, extensibility, and elasticity.

HautFingerspitzeOCT nonanimated
HautFingerspitzeOCT nonanimated

Many specialized structures live within the dermis. It houses hair follicles, sweat glands, and sebaceous glands. It also contains lymphatic vessels and blood vessels. These blood vessels provide nourishment to the dermis and the epidermis. The dermis is also where tattoo ink is held. Additionally, stretch marks are located within this layer. The hypodermis contains adipose tissue, which is body fat. This tissue provides padding and insulation. It also contains fibroblasts, macrophages, and adipocytes.

06 Hegasy Skin Layers Receptors Wiki EN CCBYSA
06 Hegasy Skin Layers Receptors Wiki EN CCBYSA

Skin pigmentation is a complex biological process. It is primarily affected by the pigment melanin. Melanocytes are specialized cells that produce melanin. This pigment absorbs potentially dangerous ultraviolet radiation (UV) from sunlight. The skin also contains DNA repair enzymes to reverse UV damage. Humans show higher skin color variation than any other mammal. This variation resulted from natural selection. Other pigments also influence color. Carotene provides yellow or orange hues. Hemoglobin and oxyhemoglobin in the blood create red or purple tones.

Rash
Rash

The scale of the skin is truly massive. For an average adult, the skin covers a large surface area. In a 70 kg male, the total skin mass is about 3.3 kg. The skin is the second largest organ in the body. The small intestine is much larger, by 15 to 20 times. The skin is a diverse habitat for life. It supports approximately 1,000 species of bacteria from nineteen phyla. Even a small area of skin is incredibly crowded. One square centimeter contains 650 sweat glands and 60,000 melanocytes. It also holds more than 1,000 nerve endings.

HautFingerspitzeOCT nonanimated
HautFingerspitzeOCT nonanimated
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