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Trematoda

life science Maturity 11-13 Next article →

Trematoda is a class of flatworms commonly known as flukes. These organisms are obligate internal parasites, meaning they must live inside a host to survive. They are known for their flattened, rhomboidal shapes. The term "trematode" comes from the Greek word "trēmatṓdēs," which means "pierced with holes." This name refers to the suckers the worms use to attach to and feed from their hosts.

TrematodesFig9 EncBrit1911
TrematodesFig9 EncBrit1911

The biology of a trematode is specialized for a parasitic life. They are usually small, often measuring only a few centimeters in length. Their bodies are covered by a tough syncytial tegument. This outer layer serves two vital purposes. First, it protects the worm from the host's digestive enzymes. Second, it acts as a surface for gas exchange because trematodes lack respiratory organs. Most flukes possess two suckers: an oral sucker near the mouth and an acetabulum on the underside. These allow them to grip host tissue firmly.

Trematodes follow incredibly complex life cycles that often require multiple hosts. Most species use an intermediate host, which is usually a mollusk like a snail. In this stage, the flukes undergo asexual reproduction to increase their numbers. After this, they must find a definitive host, which is a vertebrate. This is where sexual reproduction occurs. Some species require even more steps. For example, the oriental lung fluke, or *Paragonimus westermani*, requires three hosts. It moves from a snail to a crab or crayfish, and finally to a human or another animal.

One fascinating example of this cycle is the bird fluke, *Leucochloridium paradoxum*. This parasite uses woodland birds as its definitive host. When the adult fluke produces eggs in the bird's gut, the eggs are released through feces. If a snail swallows these eggs, the larvae, called miracidia, hatch inside. These grow into a sac-like stage called a sporocyst. The sporocyst replicates itself to produce many tiny embryos known as redia. These eventually mature into cercariae, which are ready to find a new host.

Scientists have identified between 18,000 and 24,000 species of trematodes. They are organized into two subclasses: Aspidogastrea and Digenea. The Aspidogastrea is a much smaller group with only 61 species. These flukes primarily infect bony fishes and bivalves. The Digenea subclass contains the vast majority of all trematode species. Digeneans are found in various mollusks and vertebrates. Most trematodes are monoecious, meaning they have both male and female reproductive organs. However, the blood flukes of the genus *Schistosoma* are dioecious, meaning they have separate males and females.

Many trematodes are of significant medical importance because they can cause serious diseases in humans. They are often classified by the organ systems they inhabit. Blood flukes, such as *Schistosoma haematobium*, live in the bloodstream. These can be dangerous because some species are carcinogenic, meaning they can cause cancer. The International Agency for Research on Cancer (IARC) classifies *S. haematobium* as a Group 1 carcinogen. This specific fluke can lead to bladder cancer. Other blood flukes, like *S. japonicum*, are associated with liver cancer and are classified as Group 2B carcinogens.

Other flukes target different parts of the body. Liver flukes, including *Clonorchis sinensis*, live in the bile ducts or gallbladder. These are also linked to cancer of the bile ducts. Lung flukes cause a condition called paragonimiasis. Finally, intestinal flukes inhabit the epithelium of the small intestine. These include species like *Fasciolopsis buski*, which causes fasciolopsiasis. Because trematodes can infect all five vertebrate groups—mammals, birds, amphibians, reptiles, and fish—they are a widespread part of many ecosystems.

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File:TrematodesFig9 EncBrit1911.png
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