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Mosquito-borne disease

life science Maturity 11-13

Tiny bugs can make us sick.

Dengue06.png
Dengue06.png
Mosquitoes carry germs. They pass these germs to us when they bite. This can cause a fever. It helps to stay safe. Have you ever had a bug bite?

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Mosquitoes can pass germs to people.

Dengue06.png
Dengue06.png
These germs can make us sick. Some germs are tiny living things. Others are even smaller.

One germ causes malaria. A female mosquito carries it. When she bites, the germ enters your blood.

World-map-of-past-and-current-malaria-prevalence-world-development-report-2009.png
World-map-of-past-and-current-malaria-prevalence-world-development-report-2009.png
This can cause a fever or chills.

Other mosquitoes carry different germs. These can cause yellow fever or Zika. Some people get a rash or a headache.

Child deaths from malaria number, World, 2021 (cropped).svg
Child deaths from malaria number, World, 2021 (cropped).svg

Many people get sick from these bites each year. Almost one million people die from them.

It is good to know about these bugs. Stay safe when you are outside!

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Mosquitoes can pass germs to people. These germs can be bacteria, viruses, or parasites.

Dengue06.png
Dengue06.png
Almost 700 million people get sick from these germs each year. This can lead to nearly one million deaths.

One germ is a parasite that causes malaria.

World-map-of-past-and-current-malaria-prevalence-world-development-report-2009.png
World-map-of-past-and-current-malaria-prevalence-world-development-report-2009.png
A female mosquito called Anopheles carries it. When she bites, the parasite enters the blood. It can grow inside human liver cells. Malaria is a big cause of death for young children.
Child deaths from malaria number, World, 2021 (cropped).svg
Child deaths from malaria number, World, 2021 (cropped).svg

Other mosquitoes carry viruses. These are called arboviruses.

Dengue06.png
Dengue06.png
Some viruses, like Zika, can cause a fever or a rash. Others, like dengue, can cause high fever and joint pain. In bad cases, dengue can cause bleeding inside the body.

When a mosquito bites, it lets out saliva. Your body might react to this. Bites can become itchy or red. Some people have a very strong reaction. This can cause large bumps or even blisters. It is important to know where these mosquitoes live to stay safe.

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Mosquitoes are more than just a tiny nuisance. They can carry many different kinds of germs. These germs include bacteria, viruses, and parasites.

Dengue06.png
Dengue06.png
Nearly 700 million people get sick from these illnesses every year. This can lead to almost one million deaths. Many different diseases come from mosquitoes. These include malaria, dengue, and Zika fever. There are even newer ones like the Keystone virus. It is important to understand how these germs move from insects to humans.

Transmission happens when a female mosquito bites a person. When she bites, she injects saliva and anti-coagulants into the skin.

Yellow fever Africa 2005.png
Yellow fever Africa 2005.png
This saliva helps her feed on blood. If the mosquito is carrying a germ, that germ enters the person's bloodstream. For example, the malaria parasite travels to the liver to grow. It uses liver cells as hosts to replicate and multiply. Once the parasite grows, it moves through the blood again. Then, another mosquito can bite that person and carry the parasite to someone else.

Scientists have studied these germs for a long time. In 1999, the West Nile virus was accidentally brought into the United States. By 2003, it had spread to almost every state. In 2006, there were over 3,000 cases of this virus.

World-map-of-past-and-current-malaria-prevalence-world-development-report-2009.png
World-map-of-past-and-current-malaria-prevalence-world-development-report-2009.png
Researchers also study how mosquitoes stay healthy while carrying germs. Some viruses are called arboviruses, which are viruses carried by arthropods. Mosquitoes can even use their own immune systems to chop up viral genetic code. This keeps the mosquito from getting sick while it carries the virus.

There are many important facts about these diseases. In 2012, there were 207 million cases of malaria.

Child deaths from malaria number, World, 2021 (cropped).svg
Child deaths from malaria number, World, 2021 (cropped).svg
More than half a million people died from malaria that year. By 2018, the death toll for malaria reached one million. About 120 million people live with a disability from filariasis. This is caused by a tiny worm carried by some mosquitoes. Some viruses like Zika can cause a rash or fever. Other diseases like dengue can cause internal bleeding in very bad cases.

You might recognize the feeling of a mosquito bite. Most people feel an itch or see a red bump. This is actually your immune system reacting to the mosquito's saliva.

Yellow fever South America 2005.png
Yellow fever South America 2005.png
Some people have a very strong reaction called skeeter syndrome. This can cause large blisters or bruising. Some adults do not react to bites at all. Even the way we smell can matter. A study found that some viruses change the skin bacteria of rats. This makes their body odor more attractive to mosquitoes.

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Mosquito-borne diseases are illnesses caused by bacteria, viruses, or parasites. These pathogens are transmitted to humans by mosquitoes. This is a major global health issue. Nearly 700 million people contract these illnesses every year. This results in nearly one million deaths annually. Many different types of pathogens can be carried. These include various viruses, bacteria, and even worms.

Dengue06.png
Dengue06.png

Transmission occurs when a female mosquito bites a human. During this process, the mosquito injects saliva and anti-coagulants into the skin. These substances help the mosquito feed on blood. If the mosquito is carrying a pathogen, it enters the human bloodstream during the bite. For viruses, this often involves a process called receptor-mediated endocytosis. In this process, the virus attaches to a cell surface. The host cell then ingests the viral proteins and DNA material. Once inside, the viral RNA undergoes changes to replicate and infect neighboring cells.

Yellow fever Africa 2005.png
Yellow fever Africa 2005.png

Different types of pathogens cause different diseases. Protozoa are single-celled organisms that can cause malaria. Five species of Plasmodium cause malaria in humans. These include Plasmodium falciparum and Plasmodium vivax. Bacteria can also be transmitted. For example, Mycobacterium ulcerans causes Buruli ulcer. Research from January 2024 suggests mosquitoes like Aedes notoscriptus transmit this bacterium. Some mosquitoes also carry helminths, which are parasitic worms. These worms cause filariasis, a condition that affects about 120 million people worldwide.

Yellow fever South America 2005.png
Yellow fever South America 2005.png

Viruses carried by arthropods like mosquitoes are called arboviruses. Some are specifically called moboviruses, which are mosquito-borne viruses. The Flaviviridae family includes several important viruses. This family contains the West Nile virus and the yellow fever virus. These are single-stranded, positive-sense RNA viruses. They have a protein coat and use viral antagonists to bypass the mosquito's immune system. This allows the mosquito to carry the virus without being harmed. Other viruses include Zika, dengue, and chikungunya.

World-map-of-past-and-current-malaria-prevalence-world-development-report-2009.png
World-map-of-past-and-current-malaria-prevalence-world-development-report-2009.png

Malaria is a leading cause of premature death globally. In 2012, there were an estimated 207 million cases. This resulted in more than half a million deaths. By 2018, the death toll for malaria reached one million. Children under the age of five are at particularly high risk. Other diseases have significant impacts too. West Nile virus was introduced to the United States in 1999. By 2003, it had spread to almost every state. In 2006 alone, there were over 3,000 cases reported.

Child deaths from malaria number, World, 2021 (cropped).svg
Child deaths from malaria number, World, 2021 (cropped).svg

Symptoms vary greatly depending on the specific infection. Zika virus can cause fever, rash, and joint pain. Dengue fever often involves high fever and headaches. In severe cases, dengue can lead to hemorrhagic fever and internal bleeding. Chikungunya can cause debilitating joint pain that lasts for months or years. West Nile virus symptoms can include fatigue, vomiting, and diarrhea. In serious cases, it can cause encephalitis, which is inflammation of the brain. Some people may even experience a coma or death.

Medical professionals use various methods to diagnose these illnesses. Doctors look at a patient's travel history to find potential exposures. For dengue, laboratory tests can detect the virus, though results may arrive late. West Nile virus can be confirmed through blood tests looking for antibodies. If a doctor suspects meningitis, they may perform a lumbar puncture. This involves analyzing the cerebrospinal fluid around the brain and spinal cord. For Zika, doctors must use laboratory tests on urine, saliva, or blood to confirm the infection.

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🖼️ Images & Media (5)
File:World-map-of-past-and-current-malaria-prevalence-world-development-report-2009.png
World-map-of-past-and-current-malaria-prev...
File:Dengue06.png
Dengue06.png
File:Yellow fever Africa 2005.png
Yellow fever Africa 2005.png
File:Yellow fever South America 2005.png
Yellow fever South America 2005.png
File:Child deaths from malaria number, World, 2021 (cropped).svg
Child deaths from malaria number, World,...
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