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Linus Pauling

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Linus Carl Pauling was a monumental figure in American science and global activism.

Linus Pauling 1941
Linus Pauling 1941

An American chemist and peace activist, he published over 1,200 works. Roughly 850 of these were scientific papers and books. His impact was so profound that Scientific American named him one of the 20 greatest scientists of all time. Pauling holds a unique place in history as one of only five people to win more than one Nobel Prize. He is the only person to have won two unshared Nobel Prizes. Furthermore, he is one of only two people to win Nobel Prizes in two different scientific fields.

Linus Pauling 1955a
Linus Pauling 1955a

Pauling's scientific legacy is built upon his role as a founder of two major fields: quantum chemistry and molecular biology. Quantum chemistry uses the principles of quantum mechanics to study how atoms and molecules behave. Molecular biology looks at the chemical processes within living organisms. He achieved this by combining several complex methods. He used X-ray crystallography to look at the arrangement of atoms in crystals. He also utilized molecular model building and quantum chemistry to predict how substances would act. This multi-layered approach allowed him to see the invisible world of atoms with new clarity.

One of Pauling's most vital contributions was his work on the chemical bond. A chemical bond is the force that holds atoms together to form molecules. He introduced the concept of orbital hybridization to explain how atoms share electrons. This concept describes how different types of atomic orbitals mix to create new shapes for bonding. He also developed the first accurate scale of electronegativities. Electronegativity is a measure of how strongly an atom attracts electrons in a bond. The Pauling Electronegativity Scale allowed scientists to predict the nature of chemical bonds with high precision.

Linus Pauling 1948
Linus Pauling 1948

Pauling's research into the structures of biological molecules changed how we understand life. He demonstrated the importance of the alpha helix and the beta sheet. These are specific shapes found in the secondary structure of proteins.

Helix electron density myoglobin 2nrl 17-32
Helix electron density myoglobin 2nrl 17-32

By understanding these shapes, he provided a roadmap for other researchers. His discoveries directly inspired the work of scientists like James Watson, Francis Crick, Rosalind Franklin, and Maurice Wilkins. Their subsequent work on the structure of DNA made it possible for geneticists to eventually decode the instructions for all living organisms.

His journey toward these discoveries began with a childhood fascination with chemical reactions. As a boy, he was entranced by how substances with different properties could change when mixed. He even conducted experiments using scavenged equipment from an abandoned steel plant. To fund his education, Pauling worked various jobs, including as an apprentice machinist. He eventually entered Oregon State University in 1917. He graduated in 1922 with a degree in chemical engineering. He later earned a PhD in physical chemistry and mathematical physics from the California Institute of Technology (Caltech) in 1925.

LinusPaulingGraduation1922
LinusPaulingGraduation1922

Pauling's career at Caltech was incredibly productive and marked by high-level collaboration. In 1926, he traveled to Europe to study under famous physicists like Niels Bohr and Erwin Schrödinger. This exposure to quantum mechanics became the foundation of his research. Upon returning, he became a professor at Caltech and published his most influential book, "The Nature of the Chemical Bond." This textbook is often called the "bible" of chemistry. In the 30 years following its 1939 publication, the book was cited more than 16,000 times.

Linus Pauling 1962
Linus Pauling 1962

In his later years, Pauling turned his attention to social issues and human health. He became a dedicated activist for nuclear disarmament, working to reduce the world's nuclear weapons. He also explored orthomolecular medicine, which involves using large doses of substances to treat the body. Specifically, he promoted megavitamin therapy, focusing on the use of ascorbic acid, or Vitamin C. While these medical ideas did not gain widespread acceptance in the mainstream scientific community, his commitment to peace and health remained a central part of his life. He was married to Ava Helen Pauling, a prominent human rights activist.

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🖼️ Images & Media (16)
File:Herman Henry William Pauling.jpg
Herman Henry William Pauling.jpg
File:LinusPaulingGraduation1922.jpg
LinusPaulingGraduation1922.jpg
File:Sickle Cell Blood Smear.JPG
Sickle Cell Blood Smear.JPG
File:Linus Pauling 1955a.jpg
Linus Pauling 1955a.jpg
File:Linus Pauling 1941.png
Linus Pauling 1941.png
File:Helix electron density myoglobin 2nrl 17-32.jpg
Helix electron density myoglobin 2nrl 17-32.jpg
File:Linus Pauling 1948.png
Linus Pauling 1948.png
File:Linus Pauling 1962.jpg
Linus Pauling 1962.jpg
Beckman D2 Oxygen Analyzer 2012 002 5132...
Beckman Model 735 Dissolved O2 Analyzer...
Beckman Model D Oxygen Meter with infant...
File:Letter from Ruth B. Shipley, Chief Passport Division, Department of State (United States) to Linus Pauling on February 14, 1952.jpg
Letter from Ruth B. Shipley, Chief...

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