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Digestion

life science Maturity 11-13 Vital Level 3 Next article →

Digestion is the biological process of breaking down large, insoluble food compounds. This process turns them into small, water-soluble components. Once these components are small enough, they can be absorbed into the blood plasma. Digestion is a form of catabolism, which is the breakdown of complex molecules. In many organisms, these nutrients are absorbed through the small intestine into the bloodstream. This process is vital for life because it provides the energy and materials needed for growth.

Digestive hormones
Digestive hormones

There are two distinct ways that food is broken down: mechanical and chemical digestion. Mechanical digestion is the physical breakdown of large food pieces into smaller parts. This makes it easier for digestive enzymes to access the food. Chemical digestion uses enzymes to break food down into small compounds the body can use. In humans, mechanical digestion begins in the mouth through mastication, which is the act of chewing. At the same time, saliva wets the food and provides lubrication through mucus. Saliva also contains salivary amylase, an enzyme that starts breaking down starch. About 30% of starch is hydrolyzed into disaccharides right in the oral cavity. The tongue then rolls the food into a small, round mass called a bolus.

After mastication, the bolus travels down the esophagus. It moves via peristalsis, which is a series of wave-like muscular contractions. The food then enters the stomach to meet gastric juice. This juice contains hydrochloric acid and the enzyme pepsin, which starts protein digestion. In infants and toddlers, gastric juice also contains rennin to help digest milk proteins. Because these chemicals are very strong, the stomach secretes mucus and bicarbonates. These substances create a slimy shield to protect the stomach wall from the concentrated hydrochloric acid. While proteins are being broken down, peristalsis also provides mechanical mixing in the stomach. This ensures the food mass mixes thoroughly with the digestive enzymes.

Once the food is partially digested, it is called chyme. The pyloric sphincter, a valve at the bottom of the stomach, opens to let the chyme enter the duodenum. In the duodenum, the chyme mixes with bile juice from the liver and enzymes from the pancreas. The small intestine is where the most important work happens. In fact, 95% of all nutrient absorption occurs in the small intestine. Here, pepsin breaks proteins into peptides or proteoses. These are further broken down into dipeptides and amino acids by enzymes in the small intestine.

Trophozoites of Entamoeba histolytica with ingested erythrocytes
Trophozoites of Entamoeba histolytica with ingested erythrocytes

After the small intestine, the remaining material moves into the colon, also called the large intestine. The colon has a slightly acidic pH, ranging from about 5.6 to 6.9. Its main job is to reabsorb water and minerals back into the blood. Some vitamins, such as biotin and vitamin K, are also absorbed here. These vitamins are produced by bacteria living in the colon. Finally, any waste material, known as feces, is held in the rectum. This waste is eliminated from the body during a process called defecation.

Different organisms use very different digestive strategies. Some organisms use external digestion, which developed early in evolutionary history. In this method, enzymes are secreted into the environment to break down organic material. The products then diffuse back into the organism. Most fungi rely on this method. In contrast, animals use a gastrointestinal tract for internal digestion. This is much more efficient because the animal can better control the chemical environment. It can also capture more of the broken-down products.

Venus Flytrap showing trigger hairs
Venus Flytrap showing trigger hairs

Some specialized organisms have unique ways of getting nutrients. The Venus flytrap is a plant that lives in boggy, acidic habitats. It does not eat for energy, but it uses prey to mine for nitrogen and phosphorus. Some animals have evolved specialized tools like beaks, tongues, or teeth. For example, the squid has a robust beak made of cross-linked proteins to tear prey. Birds have beaks shaped for their specific diets, like macaws that use theirs to open tough seeds. Even bacteria have complex systems, such as the type III secretion system, which acts like a molecular syringe to inject nutrients into other cells.

Conjugation
Conjugation
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File:Conjugation.svg
Conjugation.svg
File:Venus Flytrap showing trigger hairs.jpg
Venus Flytrap showing trigger hairs.jpg
File:Trophozoites of Entamoeba histolytica with ingested erythrocytes.JPG
Trophozoites of Entamoeba histolytica...
File:Abomasum-en.svg
Abomasum-en.svg
File:Flesh fly concentrating food.jpg
Flesh fly concentrating food.jpg
File:Digestive hormones.jpg
Digestive hormones.jpg
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