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Cell (biology)

life science Maturity 9-11 Vital Level 2 Next article →

The cell is the fundamental structural and functional unit of all living organisms. The term originates from the Latin word *cellula*, meaning "small room."

RobertHookeMicrographia1665
RobertHookeMicrographia1665

Cells serve as the basic building blocks for every form of life on Earth. Most cells are microscopic and require magnification to be seen. They emerged on our planet approximately four billion years ago. Almost all cells are capable of protein synthesis and replication. Only a few highly-differentiated cell types, such as red blood cells or gametes, lack these abilities.

Celltypes
Celltypes

Biologists categorize all life into two primary groups: prokaryotes and eukaryotes.

Average prokaryote cell- en
Average prokaryote cell- en

Prokaryotes are simple, single-celled organisms. This group includes the domains of bacteria and archaea. Eukaryotes are more complex and can be either single-celled or multicellular. Examples of eukaryotes include protists, plants, animals, and most fungi. All multicellular organisms are composed of many different specialized cell types. In plants and animals, the diploid cells that form the body are called somatic cells. This term excludes the haploid gametes used for reproduction.

Prokaryotic cells are characterized by their lack of a membrane-bound nucleus. Instead, their genetic material is located in an irregular region called a nucleoid.

Prokaryotes are generally smaller and simpler than eukaryotes. Most prokaryotes range from 0.5 to 2.0 micrometers in diameter. However, the largest known bacterium, *Thiomargarita magnifica*, can reach lengths of 1 to 2 centimeters. While they lack most membrane-bound organelles, some bacteria possess protein-based microcompartments. These include gas vesicles, carboxysomes, and encapsulin nanocompartments. Some specialized bacteria even possess unique organelles like magnetosomes or anammoxosomes.

Bacteria possess a complex cell envelope to protect their internal environment. This envelope typically consists of a plasma membrane and a cell wall made of peptidoglycan.

Cell membrane drawing-en
Cell membrane drawing-en

Some bacteria also have a third gelatinous layer called a capsule. This capsule may be composed of polysaccharides or polypeptides. The cell wall provides rigidity and prevents the cell from bursting due to osmotic pressure. Inside the bacterium, the DNA usually exists as a single circular chromosome. Some bacteria also carry plasmids, which are small, circular, extrachromosomal DNA molecules. These plasmids often encode helpful genes, such as those providing antibiotic resistance.

Eukaryotic cells are distinguished by a membrane-bound nucleus that houses their genetic material. The name eukaryote translates to "true nut" or "true kernel."

Structure of animal cell
Structure of animal cell

These cells can be 2 to 100 times larger than prokaryotic cells. The interior of the cell is filled with a gel-like cytoplasm. This cytoplasm contains various specialized organelles. For example, mitochondria provide necessary energy for cellular functions. In plants, chloroplasts perform photosynthesis to create sugars.

Plant cell structure-en
Plant cell structure-en

Eukaryotes also utilize an endomembrane system to modify, package, and transport proteins and lipids.

Animal cells follow specific developmental pathways to create complex bodies. All animal cells originate from a single, totipotent diploid cell called a zygote. During embryonic development, these cells undergo differentiation to become specialized tissues. This process is driven by intrinsic molecular distributions and environmental cues. Animals are often classified by the number of germ layers they possess. Sponges have only one layer, while diploblasts have two: the ectoderm and endoderm. More advanced animals are triploblastic, meaning they possess a third middle layer called the mesoderm.

Germ layers
Germ layers

The ectoderm eventually gives rise to the skin, glands, and nervous tissue.

Understanding the cell has a rich history of scientific discovery. Robert Hooke first discovered cells in 1665. He chose the name because the structures reminded him of monastery cells.

Wilson1900Fig2
Wilson1900Fig2

In 1839, scientists Matthias Jakob Schleiden and Theodor Schwann developed cell theory. This theory established three vital principles. First, all organisms are composed of one or more cells. Second, the cell is the fundamental unit of structure and function. Third, all cells arise from pre-existing cells. This discovery changed our entire understanding of biology and life.

Cells are incredibly numerous within complex organisms. For instance, the human body contains a staggering number of individual cells. An estimated 30 trillion cells make up a typical adult human. Specific estimates suggest approximately 36 trillion cells in an adult male and 28 trillion in an adult female. These cells work in harmony to maintain the functions of the entire organism. From the smallest bacterium to the largest human, the cell remains the essential unit of life.

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🖼️ Images & Media (20)
File:Symbiogenesis 2 mergers.svg
Symbiogenesis 2 mergers.svg
File:Cell membrane detailed diagram en.svg
Cell membrane detailed diagram en.svg
File:DNA structure infographic-5.svg
DNA structure infographic-5.svg
File:Cell membrane drawing-en.svg
Cell membrane drawing-en.svg
File:Three cell growth types.svg
Three cell growth types.svg
File:Average prokaryote cell- en.svg
Average prokaryote cell- en.svg
File:Plant cell structure-en.svg
Plant cell structure-en.svg
File:Celltypes.svg
Celltypes.svg
File:Diagram human cell nucleus multilang.svg
Diagram human cell nucleus multilang.svg
File:DNA replication split.svg
DNA replication split.svg
File:Binary fission.svg
Binary fission.svg
File:Structure of animal cell.JPG
Structure of animal cell.JPG

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