Nepedia
Back to Discover
Fluent Reader
🧬

Adenine

life science Maturity 11-13 Next article →

Adenine is a very important part of life.

Base pair AT
Base pair AT

It is a purine nucleotide base. This means it is a building block for many things. Most of the time, it is a white crystalline substance. You can find it in DNA and RNA.

Base pair AU
Base pair AU

It is also part of a molecule called ATP. This molecule helps living cells do their jobs. Without adenine, the tiny parts of our bodies could not work.

Adenine works by pairing up with other parts. In DNA, it binds to thymine using two hydrogen bonds. These bonds help keep the DNA structure stable.

Base pair APsi
Base pair APsi

In RNA, adenine binds to a part called uracil instead. This pairing is how the molecules hold their shape. Adenine also helps move energy around. It is part of ATP, which acts like a fuel. This fuel powers muscle contraction and nerve impulses. It even helps cells build proteins.

Scientists have studied adenine for a long time. Hermann Emil Fischer was an early scientist to look at it. Later, Albrecht Kossel named it in 1885. He chose the name from a Greek word for gland. He found his sample in a pancreas.

Template from Crick and Watson’s DNA molecular model, 1953. (9660573227)
Template from Crick and Watson’s DNA molecular model, 1953. (9660573227)

In the past, people called it Vitamin B4. Now we know it is not a vitamin. This is because our bodies can make it themselves.

There are many ways to make adenine. Inside a cell, it comes from a process called purine metabolism. It starts from a molecule called inosine monophosphate. This process uses atoms from amino acids like glycine, glutamine, and aspartic acid.

Adenosin
Adenosin

There is also a way to make it in factories. One method involves heating formamide to 120 °C. This method was patented on August 20, 1968. These facts help us understand how adenine is built.

Adenine connects to many things you might know. It works with vitamins like niacin and riboflavin. These two vitamins bind with adenine to create important helpers. These helpers are called NAD and FAD.

Adenosin
Adenosin

Scientists also study where adenine comes from. A 2011 report used NASA studies of meteorites. It suggested adenine might have formed in outer space. This means the building blocks of life could be from far away.

356 words

Where will your curiosity go next?

Keep exploring at your chosen reading level.

🖼️ Images & Media (7)
File:Base pair AT.svg
Base pair AT.svg
File:Base pair AU.svg
Base pair AU.svg
File:Base pair AD.svg
Base pair AD.svg
File:Base pair APsi.svg
Base pair APsi.svg
File:Adenosin.svg
Adenosin.svg
File:Desoxyadenosin.svg
Desoxyadenosin.svg
File:Template from Crick and Watson’s DNA molecular model, 1953. (9660573227).jpg
Template from Crick and Watson’s DNA...
More to explore

🔬 Go deeper

More advanced topics to explore

🪜 Step back

Simpler topics to build understanding

What is Nepedia?

A free, ad-free encyclopedia for children. Every article is written at five reading levels, so the same page works for a five-year-old and a fifteen-year-old — use the level switcher above to see this one change. No account needed to read.