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Shivering

life science Maturity 11-13 Next article →

Shivering, also known as shuddering, is a vital bodily function for warm-blooded animals. It serves as a defense mechanism against cold temperatures and extreme fear. The main goal of shivering is to maintain homeostasis. Homeostasis is the process of keeping the body's internal environment stable. When the core body temperature begins to drop, the shivering reflex is triggered. This reflex helps the body generate warmth through physical movement.

Winter's coming (5268496779)
Winter's coming (5268496779)

The biological process begins in a specific part of the brain. This is located in the posterior hypothalamus near the third ventricle. This area is called the primary motor center for shivering. Under normal conditions, a heat center in the anterior hypothalamic-preoptic area inhibits this center. However, cold signals from the skin and the spinal cord can excite it. When the body temperature falls even a fraction of a degree below a critical level, the center becomes activated. Once active, it causes rapid contractions of the skeletal muscles. These quick muscle movements create heat as a metabolic byproduct.

Shivering is not always caused by the external environment being cold. It can also occur as a response to a fever. During a fever, the hypothalamic set point for temperature is raised. This means the brain's internal thermostat is set to a higher level. This change causes the body temperature to rise, a condition known as pyrexia. Because the body is currently below this new, higher set point, the person feels cold. This feeling of coldness triggers the shivering response to reach the new target.

Infants and young children manage heat differently than adults do. Because they have a larger surface-area-to-volume ratio, they experience greater net heat loss. Unlike adults, young children cannot rely on shivering to maintain their body heat. Instead, they use a process called non-shivering thermogenesis. This process relies on a special type of fat called brown adipose tissue. This tissue has a high mitochondrial density and an increased vascular supply. When a child is stressed by the cold, they will have greater oxygen consumption and release norepinephrine.

The chemical process of non-shivering thermogenesis is quite complex. The norepinephrine reacts with lipases, which are enzymes, in the brown fat. This reaction breaks down the fat into triglycerides. These triglycerides are then metabolized into glycerol and non-esterified fatty acids. These components are further degraded in a heat-generating process to form carbon dioxide and water. Inside the mitochondria, a unique chemical bypass occurs. Normally, a proton gradient produces an electromotive force used to synthesize ATP. In this process, that step is bypassed to produce heat directly.

As humans age, their ability to regulate temperature changes. The functional capacity of the thermoregulatory system alters with age. This can reduce the resistance elderly people have to extreme external temperatures. In many elderly individuals, the shiver response may be greatly diminished or even absent. This lack of response can result in a significant drop in mean deep body temperature when they are exposed to the cold. The rate of decline in these thermoregulatory processes varies significantly between different individuals as they age.

Beyond temperature and fever, shivering can be linked to other states. Some people experience shivering after undergoing surgery. This specific condition is known as postanesthetic shivering. There is also a version of shivering linked to the mind rather than the body. This is called psychogenic shivering, which can be caused by cognition. It can also be a response to intense stimuli, such as music. These different types of shivering show how deeply connected our physical reflexes are to our environment, our biology, and our minds.

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File:Winter's coming (5268496779).jpg
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