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Poisoning

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Poisoning is the harmful effect that occurs when toxic substances enter a living body. A poison is any chemical substance that can harm or kill a living organism if it is ingested. This process can happen through several different pathways. A person might swallow a toxin or inhale it through the air. Toxins can also enter the body through an injection or by being absorbed through the skin.

Arsenic Poisoning
Arsenic Poisoning

Scientists study these dangerous effects through a field called toxicology. Toxicology is the practice of studying the symptoms, mechanisms, diagnoses, and treatments related to poisoning.

The severity of poisoning often depends on the level of exposure. Acute exposure occurs when an organism is harmfully exposed to a poison once or more during a brief period. In these cases, symptoms usually manifest within 14 days of the administration.

death rate from poisoning, World, 2021
death rate from poisoning, World, 2021

Chronic exposure is different because it involves exposure over an extended period of time. This happens on multiple instances over a long duration. Symptoms from chronic exposure may develop gradually or after a long latent period. This type of poisoning often involves substances that bioaccumulate or are biomagnified, such as mercury, gadolinium, or lead.

Many instances of poisoning are unintentional. According to a 2020 report from America's Poison Centers, 76.9% of recorded toxin exposures were accidental. The remaining statistics involved exposures that were either deliberate or unexpected. A large portion of these accidental incidents involve medication errors. People may mistakenly take the incorrect medicine or accidentally double a dose.

Arsenic trioxide
Arsenic trioxide

Some substances are particularly dangerous because they are difficult to identify. In 1858, a sweets poisoning incident occurred in Bradford. This happened because a substance was mistaken for a sugar substitute called "daff."

Some chemicals are engineered to be highly toxic for specific purposes. Nerve gases are synthetic substances used in industry or warfare. These are considered biologically derived neurotoxins, which are agents that act specifically against the nervous system. They can paralyze a person in seconds or cause organs to cease functioning.

Arsenic trioxide
Arsenic trioxide

Other chemicals, like the herbicide 2,4-D, are designed to target specific organisms. 2,4-D imitates the action of a plant hormone to kill plants. While it is classified as harmful, it is not technically a poison. However, people applying these biocides can still experience secondary poisoning.

Certain substances are only poisonous through a process called toxication. This means the substance is not poisonous by itself but becomes toxic after a chemical change. For example, methanol, also known as "wood alcohol," is not poisonous on its own. Once it reaches the liver, it is chemically converted into toxic formaldehyde and formic acid. Many drug molecules undergo a similar process in the liver. Because of genetic variability in liver enzymes, the toxicity of these compounds can differ between people.

To prevent accidents, government agencies use the Globally Harmonized System, or GHS, to label toxins. These labels include pictograms, which are small images that warn of danger. A common hazard symbol depicts a human skull in front of two crossed bones.

Lock Away Danger in Your Home (21247619354)
Lock Away Danger in Your Home (21247619354)

Labels also include precautionary statements that advise users to be aware of dangerous features. They may also provide instructions on how to handle the product or what compounds to avoid mixing with it.

If poisoning is suspected, seeking medical attention is strongly advised. It is helpful to contact a poison control center for assistance with diagnosis and management. When speaking to medical personnel, you should provide the patient's age, weight, and any other drugs they are taking. It is important to identify what was ingested, the amount, and how long ago the exposure happened. If possible, keep the pill bottle or medication package to show doctors.

Lock Away Danger in Your Home (21247619354)
Lock Away Danger in Your Home (21247619354)

Treatments vary depending on the substance and may include the use of activated charcoal, the induction of vomiting, or the dilution and neutralizing of the poison.

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File:Arsenic trioxide.jpg
Arsenic trioxide.jpg
File:Lock Away Danger in Your Home (21247619354).jpg
Lock Away Danger in Your Home (21247619354).jpg
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