Tiny living things are all around us. 

Tiny living things are all around us. 


Microorganisms are tiny living things. We often call them microbes. They are so small you cannot see them without help. 



Microorganisms, or microbes, are tiny living things. They can be a single cell or a group of cells called a colony. 

Microbes work in many different ways to survive. Some use light to make food like green plants. Others use chemicals in the ground to live. This way of getting energy is called chemolithotrophy. 

People suspected tiny life existed a long time ago. In 6th-century BC India, Jain literature spoke of tiny organisms. In the 1st-century BC, a Roman named Varro called them animalia minuta. 
Many famous scientists helped us understand microbes. In the 1850s, Louis Pasteur showed that microbes spoil food. 

Microbes are part of our daily lives. They help make food through a process called fermentation. 

A microorganism, often called a microbe, is a living thing of microscopic size. These organisms can exist as a single cell or as a large colony of cells. 
Microbes inhabit almost every environment on Earth. They live from the frozen poles to the hot equator. They can survive in deserts, rocks, and the deep sea. Some are extremophiles, meaning they are adapted to extreme conditions. These include very hot or very cold environments and high-pressure zones. A specific microbe called Deinococcus radiodurans can even survive in high radiation. 
Scientific understanding of these tiny organisms has evolved over many centuries. In the 6th century BC, Jain literature in India described tiny organisms called nigodas. These were thought to live in plants, animals, and people. Later, the Roman scholar Marcus Terentius Varro called unseen creatures animalia minuta. In 1546, Girolamo Fracastoro proposed that diseases were caused by transferable seedlike entities. However, the true scientific study of microbes began in the 1670s. Antonie van Leeuwenhoek used his own single-lensed microscopes to observe them for the first time. 
Several key scientists helped define the field of microbiology. In the 1850s, Louis Pasteur conducted experiments to study food spoilage. He used boiled broth and filters to prove that microbes come from the environment. This debunked the theory of spontaneous generation and supported the germ theory of disease. 

Microbes are classified into distinct groups based on their biological structures. Archaea are prokaryotic, meaning they lack a cell nucleus or membrane-bound organelles. While they were once grouped with bacteria, they are genetically and biochemically different. For example, Archaean membranes are made of ether lipids, while bacterial membranes use phosphoglycerides. 

Microorganisms play massive roles in the Earth's biological and chemical systems. They are the oldest known life forms, with evidence found in 3.45-billion-year-old Australian rocks. Prokaryotes, which include bacteria and archaea, are estimated to number around five nonillion. This accounts for at least half of the total biomass on Earth. They are essential for making soil fertile and for geochemical processes. In human culture, they are used for fermentation, treating sewage, and producing fuel. 
Finally, microbes have a profound connection to human biology and medicine. They make up the human microbiota, which includes the essential gut flora. 
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