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Lung

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The lungs are the primary organs of the respiratory system in humans and many other animals. Their main role is to perform gas exchange. This process extracts oxygen from the atmosphere and transfers it into the bloodstream. Simultaneously, the lungs release carbon dioxide from the blood back into the atmosphere.

Illu conducting passages
Illu conducting passages

In mammals, the lungs are located near the backbone on either side of the heart. They are situated within the thoracic cavity of the chest. Besides breathing, the lungs provide the airflow necessary for vocalization, which makes speech possible.

Breathing is a mechanical process driven by muscular systems. In humans, the primary muscle responsible for driving this movement is the diaphragm. The lungs are part of the lower respiratory tract. This system begins at the trachea, which is the windpipe. The trachea branches into the bronchi, which then divide into smaller tubes called bronchioles.

3D Medical Animation Bronchial Airways terminating ends
3D Medical Animation Bronchial Airways terminating ends

These airways continue to divide until the air reaches microscopic sacs called alveoli. Together, the lungs contain approximately 2,400 kilometers of airways. Within these airways, there are between 300 and 500 million alveoli where gas exchange occurs.

Alveolus diagram
Alveolus diagram

The lungs have a highly organized anatomical structure. Each lung is enclosed within a pleural sac made of two membranes called pleurae. The outer parietal pleura lines the inner chest wall. The inner visceral pleura directly lines the surface of the lung. Between these layers is the pleural cavity, which contains a thin layer of lubricating pleural fluid. This allows the lung walls to slide against each other during breathing without much friction.

Lung structure normal
Lung structure normal

The visceral pleura also forms fissures that divide the lungs into sections called lobes. The right lung is larger and heavier, containing three lobes. The left lung is smaller and contains only two lobes. This difference exists because the left lung must accommodate the heart. The left lung even features a specific indentation called the cardiac notch to make room.

Illu bronchi lungs
Illu bronchi lungs

Within these lobes, the lungs are further subdivided into smaller units. The lobes are divided into bronchopulmonary segments. These segments are further divided into even smaller lobules. Each bronchopulmonary segment is a discrete unit with its own bronchus and arterial supply. This organization is clinically important because a segment can be surgically removed without affecting surrounding tissue.

Secondary-pulmonary-lobule-illustration
Secondary-pulmonary-lobule-illustration

The right lung has more lobes and segments than the left. The left lung has a projection called the lingula, which acts as an anatomical parallel to the right lung's middle lobe.

The lungs rely on a unique, dual blood supply to function. They receive deoxygenated blood from the heart through the pulmonary circulation. This blood enters the lungs specifically to pick up oxygen. At the same time, the lungs receive a separate supply of oxygenated blood through the bronchial circulation.

Lung structure normal
Lung structure normal

The tissue itself is supported by a complex extracellular matrix. This matrix contains elastic fibers made of the protein elastin. Elastin provides the lung compliance, or elasticity, needed for the lungs to stretch and recoil during the breathing cycle. Collagen fibers also intersperse between the capillaries and the alveolar walls to provide structure.

Lung development begins during the embryonic stage. The lungs start as an outpouching of the foregut, which is the tube that forms the upper digestive system.

Gray949
Gray949

While a fetus is in the amniotic sac, the lungs do not function to breathe air. During this time, blood is diverted away from the lungs through a structure called the ductus arteriosus. Once a baby is born and begins to breathe air, this diversionary duct closes. This allows the lungs to begin the process of respiration.

Various conditions can affect the health of the respiratory tract and lung tissue. Diseases such as pneumonia and lung cancer can impact the lungs. Chronic obstructive pulmonary disease (COPD) and emphysema are other serious conditions. These chronic diseases can be related to smoking or exposure to harmful substances.

Emphysema H and E
Emphysema H and E

Additionally, bronchitis can affect the airways of the respiratory tract. Medical terminology for these subjects often uses specific roots. Terms related to the lungs frequently begin with "pulmo-", from the Latin *pulmonarius*, or "pneumo-", from the Greek word for lung.

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🖼️ Images & Media (19)
File:Illu bronchi lungs.jpg
Illu bronchi lungs.jpg
File:Lung structure normal.jpg
Lung structure normal.jpg
File:STD 190219 SWITCH Tissue 2 93x CMLE 20SNR 50IT Elastin.png
STD 190219 SWITCH Tissue 2 93x CMLE 20SNR...
File:Fibers of Collagen Type I - TEM.jpg
Fibers of Collagen Type I - TEM.jpg
File:Secondary-pulmonary-lobule-illustration.jpg
Secondary-pulmonary-lobule-illustration.jpg
File:Alveolus diagram.svg
Alveolus diagram.svg
File:3D Medical Animation Bronchial Airways terminating ends.jpg
3D Medical Animation Bronchial Airways...
File:Illu conducting passages.svg
Illu conducting passages.svg
File:3D CT of thorax, annotated.jpg
3D CT of thorax, annotated.jpg
File:Gray949.png
Gray949.png
File:ribcage during inhalation.jpg
ribcage during inhalation.jpg
File:InfarctPandLbasilarsegmentsPE.PNG
InfarctPandLbasilarsegmentsPE.PNG

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