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Longevity

life science Maturity 11-13

Some people live for a very long time.

Caçarelhos46.jpg
Caçarelhos46.jpg
They stay healthy as they get old. Good food and play help us. This is how we grow old. Do you want to live a long life?

36 words

Some people live for a very long time.

Caçarelhos46.jpg
Caçarelhos46.jpg
This is called longevity. Many things help us live longer. Our bodies have tiny plans called genes. These plans help us stay healthy. How we live also matters. Moving our bodies helps us. Eating good food is important too. In the past, many people died young. Now, people live much longer lives. Women often live longer than men. It is amazing how we grow old!
Comparison of male and female life expectancy -world.svg
Comparison of male and female life expectancy -world.svg

91 words

Longevity means living for a long time. Scientists often study life expectancy. This is the average number of years people live.

Comparison of male and female life expectancy -world.svg
Comparison of male and female life expectancy -world.svg

Many things help us live longer. Our genes, or tiny body plans, play a part. Some people have genes that help fix DNA damage. DNA is the code inside our cells.

Healthspan, parental lifespan, and longevity are highly genetically correlated.webp
Healthspan, parental lifespan, and longevity are highly genetically correlated.webp

How we live also matters a lot. This is called lifestyle. Moving our bodies helps us stay healthy. Even a little exercise can help us live longer. Eating good food is also important.

GGraphic from Ming Chinese longevity text, woodcut Wellcome L0039777.jpg
GGraphic from Ming Chinese longevity text, woodcut Wellcome L0039777.jpg

In the past, many people died young. This was often due to disease or lack of food. Today, people live much longer lives. Women often live longer than men. This may be because women have stronger immune systems. An immune system helps the body fight germs.

Caçarelhos46.jpg
Caçarelhos46.jpg

Jeanne Calment lived to be 122 years old. She is the oldest person ever found. Her age was checked with real papers.

180 words

Longevity means living for a very long time. Scientists often study life expectancy to understand this. Life expectancy is the average number of years people live.

Comparison of male and female life expectancy -world.svg
Comparison of male and female life expectancy -world.svg
This number helps us see how long people stay alive. It is a way to measure how healthy a group is. Many people wonder how we can live longer lives. Some people even write stories about living forever.

Many things work together to help a person live long. Two main factors are genetics and lifestyle. Genetics are the tiny instructions inside our cells. Scientists found that genes can help fix DNA damage. DNA is the code that tells our bodies how to grow.

Healthspan, parental lifespan, and longevity are highly genetically correlated.webp
Healthspan, parental lifespan, and longevity are highly genetically correlated.webp
Lifestyle is how we choose to live every day. Moving our bodies with exercise can help a lot. Even a little bit of exercise can add years to life. Eating well and having clean water also help us stay strong.

People have thought about long life for a very long time. In ancient times, stories told of a fountain of youth.

GGraphic from Ming Chinese longevity text, woodcut Wellcome L0039777.jpg
GGraphic from Ming Chinese longevity text, woodcut Wellcome L0039777.jpg
In the Ming period, books shared ways to stay healthy. These books used special drugs and gymnastic practices. Long ago, many people died young from disease or hunger. This was because medicine was not as good as it is now. Today, people in most places live much longer than before.

There are many real records of people who lived a long time. Jeanne Calment is the oldest person ever found. She lived to be 122 years and 164 days old.

Caçarelhos46.jpg
Caçarelhos46.jpg
Jiroemon Kimura was the oldest man ever recorded. He lived to be 116 years old. In 2010, life expectancy in Japan was about 82.84 years. In the United States, it was about 78.24 years. These numbers show how much life expectancy can change by place.

We can see how life expectancy changes between men and women. Usually, women live longer than men do. This might be because women have smaller bodies. This puts less strain on the heart. Women also tend to have stronger immune systems. An immune system is what helps the body fight germs.

Life expectancy post-COVID.png
Life expectancy post-COVID.png
This helps them stay healthy for more years. Understanding these facts helps us learn about our own bodies.

404 words

Longevity refers to the length of time an individual or a population lives. Scientists often distinguish this from life expectancy, which is a statistical average. Life expectancy represents the average number of years remaining at a specific age. For example, life expectancy at birth is the average age at death for everyone born in a single year.

Comparison of male and female life expectancy -world.svg
Comparison of male and female life expectancy -world.svg
Understanding these concepts helps researchers study how to extend human life. This subject has fascinated people for centuries, appearing in science fiction and ancient legends.

Biological longevity is driven by two primary factors: genetics and lifestyle. Genetics provide the internal blueprint for how a body ages. Studies using twins suggest that genetics account for about 20% to 30% of the variation in human lifespan. The remaining portion is determined by environmental factors and individual behaviors.

Healthspan, parental lifespan, and longevity are highly genetically correlated.webp
Healthspan, parental lifespan, and longevity are highly genetically correlated.webp
These environmental factors are often called "plastic" because they can be changed through different choices and conditions.

Research into human genetics has revealed specific mechanisms that support long life. For instance, centenarians—people who live to be 100 or older—show higher activity in a protein called PARP. This protein, known as Poly ADP ribose polymerase, helps repair DNA damage. By repairing this damage, the cells can maintain functions similar to those of younger people. Furthermore, scientists have identified genomic loci, or specific locations on a genome, that influence healthspan. Some research suggests that genes involved in metabolizing iron may also increase healthy years of life.

Lifestyle choices play a massive role in determining how long a person lives. Physical exercise is a powerful tool for increasing life expectancy. One 2012 study suggested that even modest leisure-time exercise could extend life by up to 4.5 years. Diet is another major factor, though the evidence is complex. While certain foods affect health, there is no clinical evidence that specific dietary practices or fasting promote longevity in humans. Researchers have studied caloric restriction, which is a sustained reduction in energy intake. While this helped some animals like rhesus monkeys, preliminary human research shows little evidence of a lifespan effect.

Historical data shows that human life expectancy has increased significantly over time. In preindustrial eras, many people died young due to disease, accidents, or malnutrition. Before the 20th century, many medical issues were untreatable. For example, an 1871 UK census showed a male life expectancy of only 44 years. However, if you remove infant mortality from that number, males who reached adulthood averaged 75 years. Today, life expectancy in developed nations is much higher, often ranging from 77 to 90 years.

There are several documented individuals who have set records for the longest human lifespan. Jeanne Calment is the oldest person in history whose age has been verified by modern documentation. She lived to be 122 years and 164 days old. Jiroemon Kimura holds the record for the oldest verified man, living to 116 years and 54 days. Other notable figures include Kane Tanaka, who lived to 119 years, and Sarah Knauss, the oldest American at 119 years. These individuals help scientists define the modern limits of the human life span.

Demographic differences also exist in how long different groups of people live. Women generally outlive men in most populations. This may be due to biological factors, such as women having smaller bodies that place less strain on the heart. Additionally, the X chromosome contains more genes related to the immune system, which helps women fight pathogens.

Life expectancy post-COVID.png
Life expectancy post-COVID.png
Economic and social factors also matter. In the United States, life expectancy varies by group; for example, Asian-American females average the longest lifespans, while Black American males average 69 years. This variation often reflects differences in access to healthcare, diet, and the prevalence of diseases like diabetes.

642 words
🖼️ Images & Media (7)
File:Comparison of male and female life expectancy -world.svg
Comparison of male and female life...
File:Life Expectancy in OECD.svg
Life Expectancy in OECD.svg
File:Caçarelhos46.jpg
Caçarelhos46.jpg
Healthspan, parental lifespan, and...
File:GGraphic from Ming Chinese longevity text, woodcut Wellcome L0039777.jpg
GGraphic from Ming Chinese longevity...
File:Title page of "Human Longevity" - James Easton Wellcome M0013797.jpg
Title page of "Human Longevity" - James...
File:Life expectancy post-COVID.png
Life expectancy post-COVID.png
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