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Iris (anatomy)

life science Maturity 9-11 Next article →

The iris is a thin, ring-shaped structure found in the eyes of most mammals and birds. It functions as a diaphragm to control the diameter of the pupil. The pupil acts as the eye's aperture, or opening. By adjusting the size of this opening, the iris regulates the amount of light that reaches the retina. This process is essential for vision in varying light levels. The iris also defines a person's eye color.

Iris structure
Iris structure

To manage light, the iris uses a specific muscular mechanism. The stroma, which is the front pigmented layer, contains two opposing muscle groups. The sphincter pupillae is a circular muscle located on the inner border. When it contracts, it performs a circular motion to constrict the pupil. Conversely, the dilator pupillae muscles pull the iris radially. This action enlarges the pupil by pulling the iris into folds. While the inner border of the iris changes size, the outer border remains constant.

Pupillary light reflex
Pupillary light reflex

The iris is divided into two major anatomical regions. The inner region is called the pupillary zone, and its edge forms the boundary of the pupil. The rest of the iris is the ciliary zone, which extends to the ciliary body. These two zones are separated by the collarette. The collarette is the thickest part of the iris. It is considered a vestige of the embryonic pupil coating. This area is typically where the sphincter and dilator muscles overlap.

Iris regions
Iris regions

Anatomy and development of the iris are quite complex. The stroma and the anterior border layer derive from the neural crest. Meanwhile, the muscles and the iris epithelium develop from the optic cup neuroectoderm. The iris is attached to the sclera at a point called the root. This root is the thinnest and most peripheral part of the structure. The iris and the ciliary body together form the anterior uvea.

Auge Iris
Auge Iris

Eye color is primarily determined by the pigment melanin. This pigment is produced by cells called melanocytes. There are two main types of melanin involved in human eye color. Eumelanin produces brown and black colors. Pheomelanin produces red and yellow colors. People with brown eyes have more eumelanin. People with blue or green eyes have more pheomelanin. The specific color is a result of pigment quantity and light scattering.

Light interacts with the iris in several fascinating ways. Beyond simple pigmentation, colors result from selective absorption and reflection. Processes like Rayleigh scattering and Tyndall scattering influence how we see color. These are the same physical phenomena that make the sky appear blue. In some animals, iridophores use interference effects to create brilliant colors. For humans, even babies are often born with blue eyes. This occurs because their stroma lacks pigment, leaving only light scattering.

SD OCT - Anterior Chamber Angle Cross-Section (with viewfinder)
SD OCT - Anterior Chamber Angle Cross-Section (with viewfinder)

There are several notable variations in iris appearance and function. The pupil's diameter can range from less than 2 mm to as large as 9 mm. Most humans cannot control these muscles voluntarily. However, a very few people can dilate or constrict their pupils on command. Some individuals also have a dark ring around the iris called a limbal ring. Another condition is heterochromia iridis. This occurs when the two irises are different colors, or when one iris has different colored sectors.

Heterochromia
Heterochromia
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🖼️ Images & Media (11)
File:Pupillary light reflex.jpg
Pupillary light reflex.jpg
File:Iris regions.jpg
Iris regions.jpg
File:Auge Iris.jpg
Auge Iris.jpg
File:Doppler holography of Olivier Martinache's myosis.gif
Doppler holography of Olivier...
File:Voluntary pupil dilation.gif
Voluntary pupil dilation.gif
File:SD OCT - Anterior Chamber Angle Cross-Section (with viewfinder).png
SD OCT - Anterior Chamber Angle...
File:Iris structure.png
Iris structure.png
File:Eye colors map of Europe.png
Eye colors map of Europe.png
File:Ageev iris.jpg
Ageev iris.jpg
File:Human eye with limbal ring, anterior view.jpg
Human eye with limbal ring, anterior view.jpg
File:Heterochromia.jpg
Heterochromia.jpg
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