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Folate

life science Maturity 7-9 Next article →

Folate is a vital nutrient that helps our bodies grow and stay healthy. It is also known as vitamin B9 or folacin. Because the human body cannot make folate on its own, we must get it from the food we eat.

Folate family
Folate family

This makes folate an essential nutrient for everyone. It is found naturally in many different foods. Many people also take a pill called a supplement to get enough.

GrainProducts
GrainProducts

Scientists also use a form called folic acid to strengthen foods. This process is called fortification. It is often added to wheat flour and other grains.

Folate works by helping the body perform many important tasks. It is needed to make DNA and RNA. DNA is the code that tells our cells how to work. Folate also helps the body process amino acids. These are small building blocks used for cell division.

Folic Acid Biotransformations
Folic Acid Biotransformations

This helps blood cells mature and grow correctly. Without enough folate, cells cannot divide the way they should. This can lead to a type of anemia. In this condition, red blood cells become abnormally large. People might feel tired or have shortness of breath.

Scientists discovered folate between the years 1931 and 1943. The name "folic" comes from a Latin word meaning leaf. This is because it was first found in dark-green leafy vegetables.

Folate methionine cycle
Folate methionine cycle

It is a very important medicine for the world. The World Health Organization puts it on its List of Essential Medicines. In the United States, it was the 94th most common medicine prescribed in 2023. Over 7 million prescriptions were written that year. This shows how much people rely on it for health.

There are many specific numbers to know about folate. In the U.S., adults should eat 400 micrograms of folate every day. This can come from food or from a supplement. A pregnant woman might need to take folic acid to help a baby grow. This can help prevent neural tube defects, which are problems with a baby's development. These defects include conditions like spina bifida. More than 80 countries use food fortification to help reduce these risks. Some studies show that mandatory programs can reduce spina bifida by 30 percent or more.

Folate connects to many things we see in our daily lives. You might see it in a bag of flour at the grocery store. You can find it in the green salad you eat for lunch.

GrainProducts
GrainProducts

It even connects to how doctors treat cancer. Some cancer drugs work by stopping folate from working in cells. Doctors can sometimes use a form of folate called folinic acid to help. This helps protect healthy cells from the medicine. Understanding folate helps us see how tiny nutrients keep our whole bodies running.

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🖼️ Images & Media (4)
File:Folate family.svg
Folate family.svg
File:Folic Acid Biotransformations.svg
Folic Acid Biotransformations.svg
File:Folate methionine cycle.svg
Folate methionine cycle.svg
File:GrainProducts.jpg
GrainProducts.jpg
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