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Central nervous system

life science Maturity 11-13 Next article →

The central nervous system (CNS) is the primary control and integration center for vertebrates. It consists of the brain, the spinal cord, and the retina. The CNS is responsible for coordinating the activities of the entire body. This system is found in all bilaterally symmetric and triploblastic animals. These are multicellular animals that are not sponges or diploblasts. The brain integrates incoming information and influences how the body reacts.

1202 White and Gray Matter
1202 White and Gray Matter

Protection is a vital part of how the CNS functions. The brain and spinal cord are enclosed within protective membranes called meninges. These layers act as a barrier against chemicals in the blood. This protects the brain from neurotoxins that might be found in food. Inside the meninges, the tissues are bathed in cerebral spinal fluid. This fluid replaces the extracellular fluid found in other animals. The brain sits inside the cranial cavity within the skull. The spinal cord is housed in the spinal canal within the vertebrae.

Sobo 1909 615
Sobo 1909 615

On a microscopic level, the CNS is made of two distinct types of tissue. These are known as white matter and gray matter. White matter consists of axons and oligodendrocytes. Gray matter is composed of neuron bodies and unmyelinated fibers. Both tissues contain glial cells, which are often called neuroglia. The name comes from the Greek word for "glue." These cells provide essential support to the nervous system. For example, Bergmann glia act as scaffolding for neuroblasts during neurogenesis. Microglia act as specialized macrophages to support the immune system. Astrocytes help clear metabolites and transport fuel to neurons from capillaries.

1202 White and Gray Matter
1202 White and Gray Matter

The spinal cord serves as a major pathway for communication. It starts at the base of the skull near the foramen magnum. It continues down the vertebral canal and ends near the first or second lumbar vertebra. The spinal cord receives sensory signals through afferent pathways. It sends motor signals out through efferent pathways. There are 31 pairs of spinal nerves that project from the brain stem. These nerves connect the spinal cord to the skin, joints, and muscles. Sensory information travels up through spinal tracts to the thalamus and the cortex.

Sobo 1909 615
Sobo 1909 615

The brain is the largest and most complex part of the CNS. It is divided into several functional regions. The brainstem is the first major section. It includes the medulla, the pons, and the midbrain. The medulla controls vital functions like breathing and blood pressure. The pons helps transmit information between the cerebellum and the cerebral cortex. The midbrain contains nuclei that link different parts of the motor system. It also handles parts of the visual and auditory systems. The brainstem also contains the reticular formation, which manages arousal and alertness.

1508 Autonomic Control of Pupil Size
1508 Autonomic Control of Pupil Size

Other critical regions include the cerebellum and the diencephalon. The cerebellum is located behind the pons. It controls posture, balance, and the coordination of body movements. Interestingly, the cerebellum contains more neurons than any other brain structure. The diencephalon contains the thalamus and the hypothalamus. The thalamus acts as a linkage and sorts incoming information for the cerebral hemispheres. The hypothalamus regulates primitive emotions like hunger and thirst. It also controls the secretion of hormones via the pituitary gland.

1508 Autonomic Control of Pupil Size
1508 Autonomic Control of Pupil Size

The largest visible part of the brain is the cerebrum. It is made of two cerebral hemispheres connected by the corpus callosum. The cerebrum includes the cortex, the basal ganglia, the amygdala, and the hippocampus. The cerebral cortex is the outer layer of gray matter. It is responsible for planning and carrying out everyday tasks. The hippocampus manages the storage of memories. The amygdala helps with the perception and communication of emotion. The basal ganglia are essential for the coordination of voluntary movement.

1508 Autonomic Control of Pupil Size
1508 Autonomic Control of Pupil Size

Finally, the CNS includes unique structures like the cranial nerves. There are 12 cranial nerves located in the head and neck region. While most nerves connect to the CNS through intermediaries, some connect directly. The olfactory nerves and the optic nerves are considered part of the CNS. This is because they connect directly to brain neurons without intermediate ganglia. The olfactory epithelium is unique because it is CNS tissue in direct contact with the environment. This provides a pathway for certain therapeutic agents to enter the system.

1508 Autonomic Control of Pupil Size
1508 Autonomic Control of Pupil Size
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File:1202 White and Gray Matter.jpg
1202 White and Gray Matter.jpg
File:Sobo 1909 615.png
Sobo 1909 615.png
File:1508 Autonomic Control of Pupil Size.jpg
1508 Autonomic Control of Pupil Size.jpg
File:1205 Somatic Autonomic Enteric StructuresN.jpg
1205 Somatic Autonomic Enteric StructuresN.jpg
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