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Cardiac muscle

life science Maturity 9-11 Next article →

Cardiac muscle, also known as the myocardium, is a specialized tissue that makes up the heart wall. It is one of three types of vertebrate muscle, alongside skeletal and smooth muscle. This tissue is involuntary, meaning it functions without conscious control. It is also striated, which means it has a striped appearance under a microscope.

Cardiac Muscle
Cardiac Muscle

The myocardium forms a thick middle layer. It sits between the inner endocardium and the outer epicardium. The endocardium lines the chambers and covers the valves. The epicardium is part of the pericardial sac that protects the heart.

Blausen 0470 HeartWall
Blausen 0470 HeartWall

To pump blood effectively, the muscle must contract in a complex way. The heart wall contains sheets of cardiac muscle cells called cardiomyocytes. These sheets are oriented in different directions. Some wrap around the left ventricle near the endocardium. Others are positioned closer to the epicardium. When these sheets contract together, they squeeze the heart in several directions at once. The heart becomes shorter from the apex to the base. It also becomes narrower from side to side. Finally, the muscle uses a twisting motion, similar to wringing out a damp cloth. This coordinated movement maximizes the amount of blood squeezed out during each beat.

2006 Heart Musculature
2006 Heart Musculature

At the microscopic level, cardiomyocytes have a very specific structure. Each cell is roughly 100 to 150 micrometers long and 30 to 40 micrometers wide. They are joined at their ends by intercalated discs. These discs contain gap junctions that allow ions to flow easily between cells. This creates a functional syncytium, where cells work together as a single unit.

1020 Cardiac Muscle
1020 Cardiac Muscle

Inside the cells, protein fibers called myofilaments slide past each other. These are organized into units called sarcomeres. The arrangement of actin and myosin in these sarcomeres creates the striped look.

Cardiac sarcomere structure
Cardiac sarcomere structure

To maintain this work, cells contain many mitochondria. These provide energy in the form of adenosine triphosphate, or ATP. This high energy supply makes the muscle very resistant to fatigue.

The contraction process begins with an electrical signal called an action potential. This signal travels through T-tubules, which are tiny pouches of cell membrane. These tubes run from the cell surface deep into the center. The T-tubules help transmit the signal quickly to the cell's interior. This signal triggers the release of calcium from the sarcoplasmic reticulum. This internal calcium store is located near the T-tubules. The rise in calcium causes the myofilaments to slide. This specific process is known as excitation-contraction coupling.

Myocardiocyte
Myocardiocyte

Specialized cells called pacemaker cells control the heart's rhythm. These cells can spontaneously generate electrical impulses. They also respond to signals from the brain. The primary pacemaker is the sinoatrial node. It is located on the wall of the right atrium. A secondary pacemaker is found in the atrioventricular node. Other cells, like the Purkinje fibers, are larger and conduct signals very quickly.

If this electrical coordination fails, it can lead to abnormal rhythms like ventricular fibrillation.

Supporting cells called fibroblasts are also vital to the myocardium. They do not contract like cardiomyocytes, but they create the extracellular matrix. This matrix is made of proteins like collagen and elastin. It provides strength, elasticity, and hydration to the muscle cells.

Dogcardiacmuscle400
Dogcardiacmuscle400

Fibroblasts also help repair the heart after an injury. If a person suffers a myocardial infarction, or heart attack, fibroblasts can become myofibroblasts. These cells can contract gently to pull the edges of an injury together while creating new collagen.

Maintaining the health of the cardiac muscle is essential for survival. The muscle requires a constant flow of oxygen and nutrients. This is provided by the coronary circulation. Coronary arteries originate from the aortic root and lie on the epicardial surface. These arteries bring blood into the myocardium. Afterward, coronary veins drain the blood into the right atrium. If this blood supply is restricted, it can cause ischemic conditions. These include angina or a myocardial infarction. Understanding these systems helps scientists study how to treat heart diseases.

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🖼️ Images & Media (8)
File:Blausen 0470 HeartWall.png
Blausen 0470 HeartWall.png
File:2006 Heart Musculature.jpg
2006 Heart Musculature.jpg
File:Cardiac Muscle.png
Cardiac Muscle.png
File:Cardiac sarcomere structure.png
Cardiac sarcomere structure.png
File:Myocardiocyte.png
Myocardiocyte.png
A single cardiomyocyte beating, five days...
File:1020 Cardiac Muscle.jpg
1020 Cardiac Muscle.jpg
File:Dogcardiacmuscle400.jpg
Dogcardiacmuscle400.jpg
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