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Basal ganglia

life science Maturity 9-11 Next article →

The basal ganglia are a group of clusters found deep inside the brain.

Anatomy of the basal ganglia
Anatomy of the basal ganglia

These clusters are located at the base of the forebrain and the top of the midbrain. They are very important for how we live and act every day. The basal ganglia help us choose which behaviors to perform. They make our voluntary movements smooth and easy to do. They also help us learn habits and manage our emotions.

basal-ganglia-classic
basal-ganglia-classic

Without them, our brain would have a hard job controlling our bodies.

This system works through a series of steps and connections. The largest part is the striatum, which receives signals from many different brain areas. The striatum then sends information to other parts of the basal ganglia. One part, the globus pallidus, receives these signals and sends inhibitory signals back. Inhibitory means it acts like a brake to stop certain actions.

Basal-ganglia-coronal-sections-large
Basal-ganglia-coronal-sections-large

The subthalamic nucleus helps by sending excitatory signals to the globus pallidus. This process helps the brain select the right movement at the right time.

Scientists have learned much about how these parts are built. During the development of a human embryo, the nervous system forms from three main parts. These are called the prosencephalon, mesencephalon, and rhombencephalon. The cells that form the basal ganglia move to their spots during this time. They are guided by structures called the lateral and medial ganglionic eminences.

This careful journey ensures the brain is organized correctly from the start.

There are many specific parts within the basal ganglia to know. The striatum is divided into the dorsal striatum and the ventral striatum. The dorsal part includes the caudate nucleus and the putamen. The ventral part includes the nucleus accumbens and the olfactory tubercle.

Blausen 0076 BasalGanglia
Blausen 0076 BasalGanglia

The substantia nigra is a smaller part that produces dopamine. Dopamine is a chemical messenger that is very important for balance. Other parts include the ventral pallidum and the subthalamic nucleus.

When these parts do not work correctly, it can change how a person feels or moves. For example, Parkinson's disease happens when dopamine-producing cells in the substantia nigra break down.

Motor loop
Motor loop

Huntington's disease is another condition that causes damage to the striatum. Other issues like Tourette syndrome or addiction can also be linked to these areas. Some drugs, like nicotine or cocaine, can change how the dopamine signal works. Understanding the basal ganglia helps us understand how the brain stays healthy.

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🖼️ Images & Media (8)
Anatomy of the Basal Ganglia.ogv
File:Basal-ganglia-coronal-sections-large.png
Basal-ganglia-coronal-sections-large.png
File:Anatomy of the basal ganglia.jpg
Anatomy of the basal ganglia.jpg
File:Blausen 0076 BasalGanglia.png
Blausen 0076 BasalGanglia.png
File:basal-ganglia-classic.png
basal-ganglia-classic.png
File:Motor loop.png
Motor loop.png
File:The conditional routing model.jpg
The conditional routing model.jpg
File:Basal ganglia circuits.svg
Basal ganglia circuits.svg
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