Everything is made of stuff. 

Everything is made of stuff. 
Some stuff is just one kind of thing. We call this a substance. It stays the same every time. 
A substance can be a solid or a liquid. It can even be a gas. Changing the heat can change it. For example, water can turn into steam.
Sometimes, different things mix together. This makes a mixture. You can separate a mixture back into its parts. This is not a single substance.
Pure water is a great example. It is always made of the same parts. It is a special kind of substance.
Can you find a substance in your house?
A substance is a special kind of matter. It always has the same parts. These parts are called a constant composition.
Substances can be elements. An element is a substance made of only one kind of atom. You cannot break an element down into something else. 
Substances can also be compounds. A compound is made when two or more elements join together. They do this through a chemical reaction. 
Sometimes, substances mix together. This makes a mixture. A mixture does not have the same parts every time. You can separate a mixture using simple ways. For example, you can use a magnet to pull iron out of sulfur. 
A chemical substance is a unique form of matter. It always has a constant composition, which means its parts are always the same. This substance will also show characteristic properties. These are special traits that help us identify it.
There are two main ways substances are built. One way is through elements. An element is a substance made of only one kind of atom. You cannot break an element down using a chemical reaction. 

Scientists have worked for a long time to understand these rules. In the late eighteenth century, a chemist named Joseph Proust did important work. He studied pure chemical compounds like basic copper carbonate. He found that all samples of a compound have the same proportions of elements. This idea is called the law of constant composition.
We can find many different substances in our world. There are 118 known elements in total. About 80 of these are stable, so they do not change on their own. 
It is easy to confuse a substance with a mixture. A mixture contains two or more substances that are just mixed together. They do not have a fixed composition. 
A chemical substance is a unique form of matter. It possesses a constant chemical composition and specific characteristic properties. These properties allow scientists to identify and distinguish one substance from another.
There are two primary categories of substances: elements and chemical compounds. An element is a substance made of only one kind of atom. It cannot be broken down into something else by a chemical reaction. 

Chemical compounds are further organized by their internal structures and compositions. Organic compounds are those based primarily on carbon and hydrogen atoms. Inorganic compounds include all other types of chemical compounds. Some specialized substances, called organometallic compounds, contain bonds between carbon and a metal. Compounds can also be classified by how their atoms are held together. Covalent compounds involve atoms that share electrons. Ionic compounds, often called salts, consist of oppositely charged ions. Some complex substances, known as coordination complexes, use a dative bond to hold a metal center and a ligand together.
Understanding the history of these definitions is essential to modern chemistry. In the late eighteenth century, Joseph Proust conducted important research on pure compounds. He studied substances like basic copper carbonate to understand their makeup. Proust deduced that all samples of a compound have the same proportions of elements by mass. This discovery is known as the law of constant composition. 
Chemistry uses many specific numbers to describe the world of substances. As of 2025, there are 118 known elements in the periodic table. Approximately 80 of these elements are considered stable. Stable elements do not change through radioactive decay. Pure water is a perfect example of a substance with a strict ratio. Every molecule of water contains exactly two hydrogen atoms and one oxygen atom. This 2:1 atomic ratio is a characteristic property of H2O. Other substances like refined sugar have much larger and more complex molecular formulas.
It is important to distinguish a pure substance from a chemical mixture. A mixture contains two or more substances that are combined without reacting. Mixtures do not have a fixed composition like pure substances do. 
Different scientific fields apply the term "substance" in unique ways. In geology, inorganic solid substances with uniform composition are called minerals. When minerals combine into aggregates, they are defined as rocks. In the field of law, the term can include mixtures with a defined manufacturing process. For example, charcoal is a complex mixture, but it can be identified by how it is made. Polymer chemistry also uses unique definitions for long chains of molecules. Even though polymers like polyethylene are mixtures of different molecular masses, they are defined by their specific chemical precursors.
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