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Scurvy

life science Maturity 11-13

Our bodies need special food to stay strong.

A case of Scurvy journal of Henry Walsh Mahon.jpg
A case of Scurvy journal of Henry Walsh Mahon.jpg
We get this from fruit and greens. Without it, we feel very tired. Our skin and gums can get sore. Eating oranges helps us feel better. Do you like eating fruit?

48 words

Our bodies need special food to stay strong.

A case of Scurvy journal of Henry Walsh Mahon.jpg
A case of Scurvy journal of Henry Walsh Mahon.jpg
This food is found in fruits and greens.

If we do not eat it, we get sick. We might feel very tired. Our skin and gums can get sore.

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ASM-30-325-g003.jpg

Our bodies also need this food to heal cuts. Without it, teeth can get loose. This happened to many sailors on long trips.

Eating fresh food helps us get well. Oranges and peppers are good choices. Even broccoli can help.

Eating these foods keeps us healthy and strong.

95 words

Scurvy is a sickness caused by a lack of vitamin C. Our bodies cannot make this vitamin on their own. We must get it from the foods we eat.

A case of Scurvy journal of Henry Walsh Mahon.jpg
A case of Scurvy journal of Henry Walsh Mahon.jpg

Vitamin C helps make collagen. Collagen is a protein that acts like a building block. It holds our skin, bones, and blood vessels together. Without it, our bodies cannot stay strong.

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ASM-30-325-g003.jpg

Early signs of scurvy include feeling very tired or weak. As it gets worse, gums can become sore. Teeth may even become loose. People might also see easy bruising or bleeding on their skin. In the past, this was a big problem for sailors. They were at sea for a long time without fresh food. Some voyages lost half of their crew to this disease.

Luckily, scurvy is easy to treat. Eating foods with vitamin C helps people get well. Raw citrus fruits like oranges and lemons are great. Red peppers, broccoli, and tomatoes also help. Most people feel better in just a few weeks.

Portrait of James Lind, 1716-1794, Physician at Haslar Wellcome M0003113a.jpg
Portrait of James Lind, 1716-1794, Physician at Haslar Wellcome M0003113a.jpg

185 words

Scurvy is a serious illness caused by a lack of vitamin C. This vitamin is essential for many things happening inside the human body. It helps make building blocks like collagen, carnitine, and catecholamines. Collagen is a protein that keeps our skin, bones, and blood vessels strong. Without enough vitamin C, these parts of the body can become weak or break. It usually takes at least one month without this vitamin for symptoms to appear.

A case of Scurvy journal of Henry Walsh Mahon.jpg
A case of Scurvy journal of Henry Walsh Mahon.jpg

The way scurvy works starts with a lack of energy. When the body lacks vitamin C, it cannot make enough carnitine or catecholamines. These are needed to turn food into energy called ATP. Without enough energy, people feel very tired or weak. As the sickness continues, the body cannot make strong collagen. This causes blood vessels to become fragile and leak. This leads to easy bruising, bleeding skin, and even loose teeth.

ASM-30-325-g003.jpg
ASM-30-325-g003.jpg

People have known about scurvy for a very long time. Descriptions of the sickness date back to ancient Egypt around 1550 BC. The famous Greek physician Hippocrates wrote about it too. In the later Age of Sail, scurvy was a huge problem for sailors. Many long sea voyages did not have fresh fruits or vegetables. It was often assumed that 50 percent of sailors would die from it.

Portrait of James Lind, 1716-1794, Physician at Haslar Wellcome M0003113a.jpg
Portrait of James Lind, 1716-1794, Physician at Haslar Wellcome M0003113a.jpg

There are many foods that can prevent scurvy with their high vitamin C. Red bell peppers have about 200 mg of vitamin C per 100 grams. Guava has 184 mg, and blackcurrants have 181 mg. Citrus fruits like oranges and lemons have about 53 mg. Even vegetables like broccoli and cabbage are good sources. Cooking food can sometimes decrease the amount of vitamin C left inside. Taking vitamin C supplements can also help people get better quickly.

A case of Scurvy journal of Henry Walsh Mahon.jpg
A case of Scurvy journal of Henry Walsh Mahon.jpg

Today, scurvy is much rarer than it was in the past. It mostly happens to people who do not get enough variety in their diet. This can include people living in areas with food shortages or refugees. Some people in industrialized nations might get it from poor dietary choices. You can think of vitamin C like the glue in a house. Without the glue, the walls and floors cannot stay together. Eating fresh fruits and vegetables provides the glue our bodies need.

ASM-30-325-g003.jpg
ASM-30-325-g003.jpg

404 words

Scurvy, also known as scorbutus, is a serious deficiency disease. It occurs when a person does not get enough vitamin C, which is also called ascorbic acid. This vitamin is vital for many biological processes. It acts as an antioxidant to protect cells. It also helps the intestines absorb iron from food. Humans cannot make their own vitamin C. Our livers lack the enzyme L-gulonolactone oxidase (GULO) needed to synthesize it. Because of this, we must get it from our diet. Without enough vitamin C, the body's structural integrity begins to fail.

A case of Scurvy journal of Henry Walsh Mahon.jpg
A case of Scurvy journal of Henry Walsh Mahon.jpg

The mechanism of scurvy involves several complex chemical pathways. Vitamin C is a necessary cofactor for two specific enzymes. These are prolyl hydroxylase and lysyl hydroxylase. These enzymes perform hydroxylation on the amino acids proline and lysine. This process is required to create stable collagen. Collagen is a primary structural protein in the human body. It provides strength to skin, bones, cartilage, and blood vessels. When collagen is defective, blood vessels become fragile and leak. This leads to easy bruising and internal bleeding. Furthermore, a lack of vitamin C reduces the production of carnitine and catecholamines. These substances are needed to turn food into ATP, which is the body's main energy source. Low ATP levels lead to the fatigue and weakness seen in early stages.

ASM-30-325-g003.jpg
ASM-30-325-g003.jpg

Symptoms of scurvy progress through distinct stages as the deficiency worsens. Early signs include malaise, which is a general feeling of discomfort, and lethargy. Patients may also feel weakness or soreness in their arms and legs. After one to three months of deficiency, more severe symptoms appear. These include shortness of breath and bone pain. Myalgias, or muscle pain, can occur due to low carnitine. Skin changes follow, such as roughness, easy bruising, and petechiae. Petechiae are small red spots caused by bleeding under the skin. As the disease advances, gums become diseased and teeth may loosen. Poor wound healing is also a major sign. In the late stages, patients may face jaundice, fever, or convulsions. Without treatment, scurvy is invariably fatal due to infection or bleeding.

History shows that scurvy has affected humans for thousands of years. Descriptions of the disease exist from ancient Egypt around 1550 BC. The Greek physician Hippocrates described swelling of the spleen in his writings. During the Age of Sail, scurvy was a massive threat to explorers. Sailors on long voyages often lacked fresh produce. It was often assumed that 50 percent of a crew would die from scurvy on a major voyage. This was because they relied on limited, dry staples.

Portrait of James Lind, 1716-1794, Physician at Haslar Wellcome M0003113a.jpg
Portrait of James Lind, 1716-1794, Physician at Haslar Wellcome M0003113a.jpg
Even though some people, like the monk Faxian, suggested using ginger or sea kale, many tragedies continued. This happened because fresh fruits could not be stored easily on ships.

Prevention relies on consuming foods rich in ascorbic acid. Many fruits and vegetables are excellent sources. Camu Camu contains about 2000 mg of vitamin C per 100 grams. Amla has 610 mg, and red bell peppers have 200 mg. Other good sources include guava, blackcurrants, and broccoli. Citrus fruits like oranges and lemons provide about 53 mg per 100 grams. It is important to note that cooking can decrease the amount of vitamin C in food. Eating raw fruits and vegetables is often the best way to ensure intake. In extreme cases, medical professionals use vitamin C supplements. These can be taken by mouth or intravenously for the best results. Most people begin to feel better within a few days of treatment. Full recovery usually takes only a few weeks.

In the modern world, scurvy is much rarer than in the past. It is no longer a common threat to most adults in industrialized nations. However, it still occurs in specific groups. It is often found in neglected children, the elderly living alone, or people with mental disorders. It can also affect those with alcoholism or intestinal malabsorption. Scurvy is still widespread in the developing world due to malnutrition. Among refugees, reported rates of scurvy can be between 5 and 45 percent. This shows how much food security impacts human health.

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ASM-30-325-g003.jpg

Understanding scurvy connects us to the broader study of nutrition and biochemistry. It demonstrates how a single missing micronutrient can disrupt an entire system. The disease shows how specific enzymes drive the creation of essential proteins like collagen. It also highlights the history of maritime exploration and the challenges of long-distance travel. By studying scurvy, scientists learn more about how the body uses energy and maintains its structures. It remains a powerful example of why a balanced diet is necessary for life.

778 words
🖼️ Images & Media (3)
File:ASM-30-325-g003.jpg
ASM-30-325-g003.jpg
File:Portrait of James Lind, 1716-1794, Physician at Haslar Wellcome M0003113a.jpg
Portrait of James Lind, 1716-1794,...
File:A case of Scurvy journal of Henry Walsh Mahon.jpg
A case of Scurvy journal of Henry Walsh Mahon.jpg
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