Your heart is very important. It pumps blood all around you. Sometimes the heart can get sick. We can stay healthy by eating good food. We can also play and move. Do you like to run and play?
Your heart and blood vessels are very important. They move blood through your body. Sometimes, these parts can get sick. 
Many things can cause this. Not eating enough fruits or vegetables is one. Smoking can also be bad for you. Not moving your body enough is another risk.
Eating good food helps a lot. Moving and playing can keep you strong. This helps your heart stay healthy.
Doctors can help if you get sick. Taking medicine for a sore throat can help too. Staying active is a great way to stay well.
Cardiovascular disease is a name for many sicknesses. These sicknesses affect the heart and blood vessels. Blood vessels are the tubes that carry blood. 
Some diseases affect the heart muscle. Others affect the parts that control blood flow. For example, a stroke happens in the brain. This happens because of problems with blood vessels.
Many things can lead to these sicknesses. Eating too much salt or fat is a risk. Not moving your body enough is also a risk. Smoking can cause harm to your heart too. High blood pressure is another big risk. We call high blood pressure hypertension.
Age is a very important factor. As people get older, the risk grows. Most people get these sicknesses when they are older. In the United States, 85% of people over 80 have them.
Many of these sicknesses can be stopped. You can eat healthy foods. You can also exercise to stay strong. Doctors can use medicine to help. Even treating a sore throat can help your heart later.
Cardiovascular disease is a group of many different sicknesses. These illnesses affect the heart and the blood vessels. Blood vessels are the tubes that carry blood through your body. Some diseases affect the heart muscle itself. Others affect the tubes that supply blood to the brain or legs. 
Many of these diseases work in a similar way. One common way is through atherosclerosis. This is when things build up inside the blood vessels. This buildup can be caused by high blood pressure or smoking. It can also come from things like diabetes or not exercising enough.
Scientists and doctors have studied these patterns for a long time. They have found that these diseases are changing around the world. In most developed countries, the rates have gone down since the 1970s. However, deaths from these diseases are increasing in much of the developing world. In 2015, cardiovascular disease caused 17.9 million deaths globally. This was a big increase from the 12.3 million deaths in 1990. Researchers now know that many of these deaths are preventable.
There are many facts about who gets these diseases. Age is one of the most important factors. The risk of heart disease can triple every ten years as you get older. In the United States, 11% of people aged 20 to 40 have these diseases. That number jumps to 85% for people over age 80.
It is helpful to think of your heart like a machine that needs care. You can protect it by making good choices every day. Eating healthy foods with less salt and fat is a great start. Moving your body for 150 minutes of moderate activity each week helps too. Avoiding tobacco smoke is another way to keep your blood vessels clear. 
Cardiovascular disease (CVD) refers to any medical condition that affects the heart or the blood vessels. This group of diseases is significant because it is the leading cause of death worldwide, except in Africa. In 2015, CVD caused 17.9 million deaths, which accounted for 32.1% of all deaths globally. This was a notable increase from 1990, when CVD caused 12.3 million deaths.
A major mechanism in many cardiovascular diseases is atherosclerosis. This process involves the buildup of substances within the walls of the arteries. This buildup can lead to coronary artery disease, stroke, and peripheral artery disease. Several factors contribute to this process, including high blood pressure, smoking, and diabetes mellitus. Obesity, a poor diet, and a lack of exercise also play roles. High blood cholesterol and excessive alcohol consumption are further contributing factors. When these processes occur, they can restrict the flow of blood through the body.
Cardiovascular diseases are categorized by which part of the system they affect. Vascular diseases involve the blood vessels. These include coronary artery disease, which affects the heart's vessels, and cerebrovascular disease, which affects the brain. Stroke is a type of cerebrovascular disease. Other vascular examples include peripheral arterial disease in the limbs and renal artery stenosis in the kidneys. There are also many diseases that affect the heart itself. Cardiomyopathy involves the heart muscle, while arrhythmia refers to abnormalities in the heart rhythm. Valvular heart disease affects the heart's valves, and endocarditis is an inflammation of the heart's inner layer.
Certain diseases have specific causes or origins. For example, rheumatic heart disease can follow an untreated strep throat infection caused by Streptococcus pyogenes. This infection can damage the heart muscles and valves. Another type is congenital heart disease, which refers to malformations of the heart structure that exist at birth. Myocarditis is an inflammation of the heart muscle, often caused by viral infections. This condition is characterized by the infiltration of white blood cells, such as lymphocytes and monocytes, into the heart tissue. 
Risk factors for CVD are divided into two main groups: modifiable and immutable. Immutable factors are those that cannot be changed, such as age, sex, and genetic predisposition. Age is the most significant risk factor, as the risk of developing CVD triples with each decade of life. Genetics also play a role; having a parent with CVD increases a person's risk by approximately three times. Most common cardiovascular diseases are non-Mendelian, meaning they are influenced by hundreds or thousands of small genetic variants. Modifiable factors are those that can be changed through lifestyle or medical treatment. These include tobacco use, physical inactivity, and diet.
Specific statistics highlight the impact of lifestyle and biological factors. Dietary risk factors are associated with 53% of CVD deaths. High blood pressure accounts for about 13% of deaths, while tobacco use accounts for 9%. Diabetes and a lack of exercise each account for 6% of deaths. Obesity is associated with 5% of deaths. Physical inactivity is a major concern, as it is the fourth leading risk factor for mortality worldwide. Conversely, participating in 150 minutes of moderate physical activity each week can reduce the risk of ischemic heart disease and diabetes by almost a third.
Biological differences between sexes also influence CVD risk. At the same age, men are about 50% more likely to develop CVD than women. Men are also typically diagnosed seven to ten years earlier. One proposed reason for this is the protective effect of estrogen in women. Estrogen may improve endothelial cell function and glucose metabolism. However, after menopause, estrogen levels decrease, which can change lipid metabolism. In women, high blood pressure combined with pregnancy complications can triple the risk of CVD.
Prevention remains a critical goal, as it is estimated that up to 90% of CVD may be preventable. Improving risk factors through healthy eating and regular exercise is highly effective. Avoiding tobacco smoke and limiting alcohol intake also reduces danger. Medical treatments for high blood pressure, diabetes, and high blood lipids are beneficial. For instance, treating strep throat with antibiotics can decrease the risk of rheumatic heart disease. While some treatments like aspirin are used, their benefit for otherwise healthy people remains unclear. By managing these factors, the global burden of cardiovascular disease can be reduced.
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